Evidence map›Paper›PMID 33523304›Full record

ReviewEuropean radiology2021

Consensus report from the 9

Dow-Mu Koh, Ahmed Ba-Ssalamah, Giuseppe Brancatelli, Ghaneh Fananapazir, M Isabel Fiel, Satoshi Goshima, Sheng-Hong Ju, Nikolaos Kartalis, Masatoshi Kudo, Jeong Min Lee and 9 more

Registry-linked trialOpen access · hybridAbstract readConsensus StatementReview
In one paragraph

Review in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05314400 (A Prospective Study Evaluating Diagnostic Accuracy, Outcome, and Economic Impact of Abbreviated Gadoxetate-enhanced MRI of the Liver in Patients With Metastatic Colorectal Carcinoma), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05314400 narecruitingnot on this mapstarted 2022, after this paper: background citation

A Prospective Study Evaluating Diagnostic Accuracy, Outcome, and Economic Impact of Abbreviated Gadoxetate-enhanced MRI of the Liver in Patients With Metastatic Colorectal Carcinoma

TypeinterventionalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2022 to 2027Enrolled200ConditionsLiver Metastasis Colon CancerArmsFull Gadoxetate-enhanced liver MRI, Shortened Gadoxetate-enhanced liver MRI
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  14. [Standardized screening and early imaging diagnosis strategies for hepatocellular carcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 15 institutions in 10 countries.

Dow-Mu KohDepartment of Diagnostic Radiology, Royal Marsden Hospital, Sutton, UK. Mu.Koh@icr.ac.uk.ORCID http://orcid.org/0000-0001-7654-8011
Ahmed Ba-SsalamahDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Giuseppe BrancatelliDipartimento di Biomedicina, Neuroscienze e Diagnostica avanzata (BiND), University of Palermo, Palermo, Italy.
Ghaneh FananapazirDepartment of Radiology, Mayo Clinic Arizona, Phoenix, AZ, USA.
M Isabel FielDepartment of Pathology, Molecular and Cell Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Satoshi GoshimaDepartment of Diagnostic Radiology & Nuclear Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Sheng-Hong JuDepartment of Radiology, Zhongda Hospital, Southeast University, Nanjing, People's Republic of China.
Nikolaos KartalisDepartment of Radiology Huddinge, Karolinska University Hospital, Stockholm, Sweden.
Masatoshi KudoDepartment of Hepatology and Gastroenterology, Kindai University Faculty of Medicine, Osaka, Japan.
Jeong Min LeeDepartment of Radiology, College of Medicine, Seoul National University, Seoul, South Korea.
Takamichi MurakamiDepartment of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan.
Max SeidenstickerKlinik und Poliklinik für Radiologie, Klinikum der Universität München, Munich, Germany.
Claude B SirlinDepartment of Radiology, University of California San Diego, San Diego, CA, USA.
Cher Heng TanDepartment of Diagnostic Radiology, Tan Tock Seng Hospital, Lee Kong Chian School of Medicine, Singapore, Singapore.
Jin WangDepartment of Radiology, Third Affiliated Hospital of Sun Yat Sen University, Guangzhou, People's Republic of China.
Jeong Hee YoonDepartment of Radiology, College of Medicine, Seoul National University, Seoul, South Korea.
Mengsu ZengDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Jian ZhouLiver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Bachir TaouliDepartment of Diagnostic, Molecular, and Interventional Radiology, BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sun Yat-sen University · CNIcahn School of Medicine at Mount Sinai · USSeoul National University · KRHamamatsu University School of Medicine · JPKarolinska University Hospital · SEKindai University · JPKobe University · JPLMU Klinikum · DEMayo Clinic Hospital · USMedical University of Vienna · ATRoyal Marsden NHS Foundation Trust · GBTan Tock Seng Hospital · SGUniversity of California San Diego · USUniversity of Palermo · ITZhongda Hospital Southeast University · CN

Funding

Bayer This study received funding from Bayer AG. No complex statistical methods were necessary for this paper. Institutional Review Board approval was not required because this is a review paper. Medical writing assistance was provided by Bill Wolvey at Parexel, and was funded by Bayer AG
6 · The paper itself

Abstract

objectivesThe 9th International Forum for Liver Magnetic Resonance Imaging (MRI) was held in Singapore in September 2019, bringing together radiologists and allied specialists to discuss the latest developments in and formulate consensus statements for liver MRI, including the applications of gadoxetic acid-enhanced imaging.

methodsAs at previous Liver Forums, the meeting was held over 2 days. Presentations by the faculty on days 1 and 2 and breakout group discussions on day 1 were followed by delegate voting on consensus statements presented on day 2. Presentations and discussions centered on two main meeting themes relating to the use of gadoxetic acid-enhanced MRI in primary liver cancer and metastatic liver disease. RESULTS AND

conclusionsGadoxetic acid-enhanced MRI offers the ability to monitor response to systemic therapy and to assist in pre-surgical/pre-interventional planning in liver metastases. In hepatocellular carcinoma, gadoxetic acid-enhanced MRI provides precise staging information for accurate treatment decision-making and follow-up post therapy. Gadoxetic acid-enhanced MRI also has potential, currently investigational, indications for the functional assessment of the liver and the biliary system. Additional voting sessions at the Liver Forum debated the role of multidisciplinary care in the management of patients with liver disease, evidence to support the use of abbreviated imaging protocols, and the importance of standardizing nomenclature in international guidelines in order to increase the sharing of scientific data and improve the communication between centers. KEY POINTS: • Gadoxetic acid-enhanced MRI is the preferred imaging method for pre-surgical or pre-interventional planning for liver metastases after systemic therapy. • Gadoxetic acid-enhanced MRI provides accurate staging of HCC before and after treatment with locoregional/biologic therapies. • Abbreviated protocols for gadoxetic acid-enhanced MRI offer potential time and cost savings, but more evidence is necessary. The use of gadoxetic acid-enhanced MRI for the assessment of liver and biliary function is under active investigation.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsConsensusContrast MediaGadolinium DTPAHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyRetrospective StudiesSensitivity and SpecificityContrast MediaGadolinium DTPAgadolinium ethoxybenzyl DTPAGadoxetic acidHepatocellular carcinomaMagnetic resonance imagingMetastatic liver disease

Identifiers

PMID33523304
PMCPMC8270799
OpenAlexW3126498220

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.