ArticleThe Angle orthodontist2021
Genetic and environmental components of vertical growth in mono- and dizygotic twins up to 15-18 years of age.
Article in The Angle orthodontist, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Artificial intelligence for craniofacial and mandibular growth prediction: A systematic review.Clinical oral investigations · 2026Pooled it
- Do patients with different craniofacial patterns have differences in upper airway volume? A systematic review with network meta-analysis.European journal of orthodontics · 2024Pooled it
- Factors Associated with Lip-Closing Strength in Children Undergoing Orthodontic Assessment: A Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2026Article
- Comparison of individualized facial growth prediction models using artificial intelligence and partial least squares based on the Mathews growth collection.The Angle orthodontist · 2025Article
- Prevalence of Malocclusions among Schoolchildren from Southwestern Romania.Diagnostics (Basel, Switzerland) · 2024Article
- Comparison of individualized facial growth prediction models based on the partial least squares and artificial intelligence.The Angle orthodontist · 2024Article
- Evaluation of an individualized facial growth prediction model based on the multivariate partial least squares method.The Angle orthodontist · 2022Article
- Influence of genotype and perioral musculature on maxillary and mandibular development.The Angle orthodontist · 2022Article
- Three-Dimensional Analysis of Posterior Mandibular Displacement in Rats.Veterinary sciences · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine the additive genetic and environmental contributions to the vertical growth of craniofacial structures. MATERIALS AND
methodsThe sample consisted of 64 untreated monozygotic (44 male, 20 female) and 61 untreated dizygotic twins (32 male, 29 female). Lateral cephalograms taken at 15 and 18 years of age were traced to analyze the sella-nasion-nasal line angle (SN-NL), nasal line-mandibular line angle (ML-NL), sella-nasion-mandibular line angle (SN-ML), sella-nasion-sella-gnathion angle (Y-axis), posterior face height/anterior face height (PFH/AFH), and lower anterior face height/anterior face height (LAFH/AFH). The genetic and environmental components of variance were analyzed with structural equation modeling for multilevel mixed effects.
resultsAt 15 years of age, strong dominant genetic control was seen for NL-ML (81%), LAFH/AFH (73%), and Y-axis (57%), whereas strong additive genetic components were found for PFH/AFH (78%), SN-NL (58%), and SN-ML (57%). Unique environmental factors accounted for 18-42% of observed variance, with SN-NL being affected the most (42%). At 18 years of age, only LAFH/AFH (86%) was under strong dominant genetic control, whereas the remainder were under additive genetic influence. The sole exception was SN-NL, which changed from additive to unique environmental influence.
conclusionsEither additive or dominant genetic components were found at 15 or 18 years of age for most vertical variables. Environmental factors accounted for about 10-40%, with SN-NL being mostly affected.
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