ArticleeLife2021
Performance in even a simple perceptual task depends on mouse secondary visual areas.
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- How perceptual learning rewires brain connectivity: lessons from the visual system in a top-down perspective.Frontiers in neural circuits · 2025Pooled it
- A standardized and reproducible behavioral framework to elicit multiple aspects of visual spatial attention in mice.Cell reports methods · 2026Article
- Ecological Visual Processing in the Mouse.Annual review of neuroscience · 2026Review
- Causal and directional elements of global brain dynamics.bioRxiv : the preprint server for biology · 2026Article
- Readout and delayed transmission of initial afferent V1 activity in decisions about stimulus contrast.eLife · 2026Article
- Context-dependent activation of V1 parvalbumin interneurons enhances visual discrimination.PLoS biology · 2025Article
- Recurrent cortical networks encode natural sensory statistics via sequence filtering.bioRxiv : the preprint server for biology · 2025Article
- Touch-driven advantages in reaction time but not in performance in a cross-sensory comparison of reinforcement learning.Heliyon · 2025Article
- Cellular-resolution optogenetics reveals attenuation-by-suppression in visual cortical neurons.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- An essential role for the latero-medial secondary visual cortex in the acquisition and retention of visual perceptual learning in mice.Nature communications · 2024Article
- Network influence determines the impact of cortical ensembles on stimulus detection.bioRxiv : the preprint server for biology · 2024Article
- Single-cell optogenetics reveals attenuation-by-suppression in visual cortical neurons.bioRxiv : the preprint server for biology · 2024Article
- Stimulus-dependent differences in cortical versus subcortical contributions to visual detection in mice.Current biology : CB · 2024Article
- The influence of cortical activity on perception depends on behavioral state and sensory context.Nature communications · 2024Article
- Efficient coding of natural images in the mouse visual cortex.Nature communications · 2024Article
- Article
- Visual experience induces 4-8 Hz synchrony between V1 and higher-order visual areas.Cell reports · 2023Article
- Excitation creates a distributed pattern of cortical suppression due to varied recurrent input.Neuron · 2023Article
- Amplified cortical neural responses as animals learn to use novel activity patterns.Current biology : CB · 2023Article
- Narrowband gamma oscillations propagate and synchronize throughout the mouse thalamocortical visual system.Neuron · 2023Article
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Authors and funding
4 authors.
Funding
Abstract
Primary visual cortex (V1) in the mouse projects to numerous brain areas, including several secondary visual areas, frontal cortex, and basal ganglia. While it has been demonstrated that optogenetic silencing of V1 strongly impairs visually guided behavior, it is not known which downstream areas are required for visual behaviors. Here we trained mice to perform a contrast-increment change detection task, for which substantial stimulus information is present in V1. Optogenetic silencing of visual responses in secondary visual areas revealed that their activity is required for even this simple visual task. In vivo electrophysiology showed that, although inhibiting secondary visual areas could produce some feedback effects in V1, the principal effect was profound suppression at the location of the optogenetic light. The results show that pathways through secondary visual areas are necessary for even simple visual behaviors.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.