Evidence map›Paper›PMID 33522461›Full record

ArticleJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc2021

Evaluation of a real-time RT-PCR panel for detection of SARS-CoV-2 in bat guano.

Eman Anis, Greg Turner, Julie C Ellis, Andrew Di Salvo, Amanda Barnard, Susan Carroll, Lisa Murphy

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Eman AnisDepartment of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, New Bolton Center, Kennett Square, PA.ORCID https://orcid.org/0000-0002-2084-1902
Greg TurnerPennsylvania Game Commission, Bureau of Wildlife Management, Harrisburg, PA.
Julie C EllisNortheast Wildlife Disease Cooperative, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA.
Andrew Di SalvoPennsylvania Game Commission, Bureau of Wildlife Management, Harrisburg, PA.
Amanda BarnardDepartment of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, New Bolton Center, Kennett Square, PA.
Susan CarrollDepartment of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, New Bolton Center, Kennett Square, PA.
Lisa MurphyDepartment of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, New Bolton Center, Kennett Square, PA.
University of Pennsylvania · USPennsylvania Fish and Boat Commission · USUniversity of Sadat City · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is an ongoing global health concern. The exact source of the virus has not been identified, but it is believed that this novel coronavirus originated in animals; bats in particular have been implicated as the primary reservoir of the virus. SARS-CoV-2 can also be transmitted from humans to other animals, including tigers, cats, and mink. Consequently, infected people who work directly with bats could transfer the virus to a wild North American bat, resulting in a new natural reservoir for the virus, and lead to new outbreaks of human disease. We evaluated a reverse-transcription real-time PCR panel for detection of SARS-CoV-2 in bat guano. We found the panel to be highly specific for SARS-CoV-2, and able to detect the virus in bat guano samples spiked with SARS-CoV-2 viral RNA. Our panel could be utilized by wildlife agencies to test bats in rehabilitation facilities prior to their release to the wild, minimizing the risk of spreading this virus to wild bat populations.

Indexed as

AnimalsAnimals, WildChiropteraCOVID-19FecesHumansReal-Time Polymerase Chain ReactionSARS-CoV-2Sensitivity and SpecificityZoonosesbat guanocoronavirusCOVID-19RT-rtPCRSARS-CoV-2

Identifiers

PMID33522461
PMCPMC7953109
OpenAlexW3126926766

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.