Observational studyJournal of child neurology2021
Deep Medullary Vein White Matter Injury Global Severity Score Predicts Neurodevelopmental Impairment.
Observational study in Journal of child neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The trial behind it
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Deep medullary vein thrombosis in neonates: a retrospective study.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Venous-significant intracranial hemorrhage in neonatal HIE treated with therapeutic hypothermia: imaging phenotypes, diagnostic pitfalls, and prognostic implications.Frontiers in neuroscience · 2026Review
- MRI evaluation of ADC values and venous variations in fetal cerebral white matter with T2WI signal hyperintensity in late gestation.Frontiers in medicine · 2026Article
- Radiographic Severity of Neonatal Deep Medullary Venous Thrombosis is Associated with Neurodevelopmental Impairment.The Journal of pediatrics · 2025Article
- Cerebral venous thrombosis and deep medullary vein thrombosis: Padua experience over the last two decades.European journal of pediatrics · 2024Article
- A radiomics-based study of deep medullary veins in infants: Evaluation of neonatal brain injury with hypoxic-ischemic encephalopathyFrontiers in neuroscience · 2022Article
- Research advances in neonatal cerebral sinovenous thrombosis.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
aimTo examine associations between the deep medullary vein white matter injury global severity scoring system and neurodevelopmental impairment.
methodsThis is a prospective observational cohort study of infants born at ≥32 weeks, diagnosed with deep medullary vein thrombosis and infarction on neuroimaging in the first month of life. Developmental testing was performed using validated measures for early, preschool, and school-age follow-up.
resultsNineteen (37%) patients had major neurodevelopmental impairment. Global severity score was higher among patients with neurodevelopmental impairment (21.6 vs 13.4,
conclusionsResults suggest a need for targeted clinical surveillance for patients with a high global severity score and/or asymmetric, predominantly right cerebral white matter injury and for those who develop epilepsy.
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Registered trials
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