Evidence map›Paper›PMID 33522282›Full record

SynthesisAnnals of medicine2021

Association between apnea-hypopnea index and coronary artery calcification: a systematic review and meta-analysis.

Wen Hao, Xiao Wang, Jingyao Fan, Yaping Zeng, Hui Ai, Shaoping Nie, Yongxiang Wei

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Annals of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06766760 (A Pilot Study of Single-port Robot-assisted Surgery Using da Vinci SP Surgical System for the Surgical Treatment for Patients With Obstructive Sleep Apnea), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06766760 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Pilot Study of Single-port Robot-assisted Surgery Using da Vinci SP Surgical System for the Surgical Treatment for Patients With Obstructive Sleep Apnea

TypeinterventionalSponsorChang Gung Memorial HospitalRan2025 to 2026Enrolled25ConditionsObstructive Sleep ApneaArmsDa Vinci SP Surgical System, Model SP1098
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wen HaoEmergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Xiao WangEmergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Jingyao FanEmergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yaping ZengEmergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Hui AiEmergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Shaoping NieEmergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yongxiang WeiBeijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China.
Beijing Anzhen Hospital · CNCapital Medical University · CNBeijing Institute of Water · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study aimed to evaluate the association between presence and severity of obstructive sleep apnoea (OSA) and the presence of subclinical coronary artery disease (CAD) as assessed by coronary calcium score.

methodsMedline, Cochrane, and Google Scholar databases were searched. The presence of coronary artery calcification (CAC) and CAC score were assessed.

resultsIrrespective of the cut-off value of apnoea-hypopnea index (AHI) (5 or 15 events/h), patients in the OSA group had higher rate of CAC presence and mean CAC score than those in the control group. Subgroup analyses of patients monitored with home sleep apnoea testing (HSAT) or in-hospital/laboratory polysomnography showed that the OSA group had higher rate of CAC presence and mean CAC score than the control group, except in the comparison of mean CAC score between AHI ≥5 vs. <5 events/h for patients using HSAT, which was not significant. Pair-wise comparison showed that CAC score may increase with increased OSA severity.

conclusionsIn participants without symptomatic coronary disease, the presence of OSA was associated with the presence and extent of CAC. However, potential confounders such as age, gender, and BMI and the diversity of CAC scores may affect the association.

Indexed as

Severity of Illness IndexAdultAgedCoronary Artery DiseaseCoronary VesselsFemaleHumansMaleMiddle AgedPolysomnographyReference ValuesSleep Apnea, ObstructiveVascular Calcificationapnoea-hypopnea indexcoronary artery calcificationcoronary calcium scoreObstructive sleep apnoeasubclinical coronary artery disease

Identifiers

PMID33522282
PMCPMC7877988
OpenAlexW3126741171

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.