Evidence map›Paper›PMID 33522245›Full record

ArticleCirculation. Genomic and precision medicine2021

Genetic Predictor to Identify Individuals With High Lipoprotein(a) Concentrations.

Jacqueline S Dron, Minxian Wang, Aniruddh P Patel, Uri Kartoun, Kenney Ng, Robert A Hegele, Amit V Khera

Open access · bronzeAbstract readLetter
In one paragraph

Article in Circulation. Genomic and precision medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Genetic Prediction of Circulating Lipoprotein(a) Levels in Diverse Populations.medRxiv : the preprint server for health sciences · 2026
    Article
  3. KILDA: identifying KIV-2 repeats from kmers.NAR genomics and bioinformatics · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jacqueline S Dron *Robarts Research Institute (J.S.D., R.A.H.), Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Minxian Wang *Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA (J.S.D., M.W., A.P.P., A.V.K.).
Aniruddh P PatelCenter for Genomic Medicine (J.S.D., A.P.P., A.V.K.), Massachusetts General Hospital, Boston.
Uri KartounCenter for Computational Health, IBM Research, Cambridge, MA (U.K., K.N.).
Kenney NgCenter for Computational Health, IBM Research, Cambridge, MA (U.K., K.N.).
Robert A HegeleRobarts Research Institute (J.S.D., R.A.H.), Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Amit V KheraCenter for Genomic Medicine (J.S.D., A.P.P., A.V.K.), Massachusetts General Hospital, Boston.
Broad Institute · USCenter for Environmental Health · USWestern University · CA

Funding

Center for Common Disease GeneticsUM1HG008895 · NHGRI · BROAD INSTITUTE, INC. · PI DALY, MARK JOSEPH, GABRIEL, STACEY · 2016 to 2020
$111.2M
MULTIDISCIPLINARY RESEARCH TRAINING IN CARDIOLOGYT32HL007208 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Patrick Thomas Ellinor, David E Sosnovik · 1985 to 2026
$16.1M
Polygenic prediction of common, complex diseasesK08HG010155 · NHGRI · MASSACHUSETTS GENERAL HOSPITAL · PI KHERA, AMIT VIKRAM · 2018 to 2021
$1.1M
CIHRNHGRI NIH HHS K08 HG010155NHGRI NIH HHS UM1 HG008895NHLBI NIH HHS T32 HL007208
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biological Specimen BanksBiomarkersCardiovascular DiseasesGenetic Predisposition to DiseaseGenome-Wide Association StudyGenotypeHumansLipoprotein(a)United KingdomWhite PeopleBiomarkersLipoprotein(a)biomarkerscholesterolgeneticsgenetic testinghumans

Identifiers

PMID33522245
PMCPMC7887018
OpenAlexW3126648120

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.