Evidence map›Paper›PMID 33521937›Full record

ArticleEuropean journal of immunology2021

MHC Class I on murine hematopoietic APC selects Type A IEL precursors in the thymus.

S Thera Lee, Hristo Georgiev, Elise R Breed, Roland Ruscher, Kristin A Hogquist

Open access · bronzeAbstract read
In one paragraph

Article in European journal of immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Thymic Dendritic Cells Revisited.Immunological reviews · 2025
    Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

S Thera LeeCenter for Immunology and Department of Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, MN, 55455.
Hristo GeorgievCenter for Immunology and Department of Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, MN, 55455.ORCID 0000-0003-1369-960X
Elise R BreedCenter for Immunology and Department of Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, MN, 55455.
Roland RuscherCenter for Immunology and Department of Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, MN, 55455.
Kristin A HogquistCenter for Immunology and Department of Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, MN, 55455.ORCID 0000-0001-9963-5687
University of Minnesota · US

Funding

IMMUNOLOGY TRAINING PROGRAMT32AI007313 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Carla Rothlin · 1989 to 2026
$5.7M
TCR signal strength in thymic selectionR37AI039560 · NIAID · UNIVERSITY OF MINNESOTA · PI HOGQUIST, KRISTIN A. · 2012 to 2021
$3.7M
Stem Cell Biology Training ProgramT32GM113846 · NIGMS · UNIVERSITY OF MINNESOTA · PI PERLINGEIRO, RITA C. R. · 2015 to 2019
$712k
Contribution of antigen presenting cells to thymic negative selectionF30AI131483 · NIAID · UNIVERSITY OF MINNESOTA · PI BREED, ELISE R · 2017 to 2020
$151k
NIAID NIH HHS F30 AI131483NIAID NIH HHS R37 AI039560NIAID NIH HHS T32 AI007313NIGMS NIH HHS T32 GM113846
6 · The paper itself

Abstract

TCRαβ

Indexed as

Clonal Selection, Antigen-MediatedLymphopoiesisAnimalsBiomarkersCell DifferentiationGenes, MHC Class IImmunophenotypingIntraepithelial LymphocytesMicePrecursor Cells, T-LymphoidThymocytesThymus GlandBiomarkersAPCIELMHC class IThymus

Identifiers

PMID33521937
PMCPMC9846822
OpenAlexW3127060461

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.