Evidence map›Paper›PMID 33521703›Full record

ReviewTechniques and innovations in gastrointestinal endoscopy2021

Stay (GI) Healthy: COVID-19 and Gastrointestinal Manifestations.

Edoardo Vespa, Nicola Pugliese, Francesca Colapietro, Alessio Aghemo

Erratum issuedOpen access · bronzeAbstract readReview
In one paragraph

Review in Techniques and innovations in gastrointestinal endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Gastrointestinal and sensory manifestations, nutrition management, and energy-protein intake in hospitalized patients with COVID-19.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2022
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Comparative Anti-Inflammatory Effects ofInternational journal of molecular sciences · 2021
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Edoardo VespaInternal Medicine and Hepatology Unit, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Nicola PuglieseInternal Medicine and Hepatology Unit, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Francesca ColapietroInternal Medicine and Hepatology Unit, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Alessio AghemoInternal Medicine and Hepatology Unit, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Humanitas University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 is the virus responsible for COVID-19, whose clinical spectrum ranges widely, both in terms of severity and multi-organicity. SARS-CoV-2 mainly involves the respiratory tract, causing from a flu-like syndrome to interstitial pneumonia and acute respiratory distress syndrome. Although its entry receptor, angiotensin-converting-enzyme 2, is typically expressed in epithelial cells of the airways, extra-pulmonary involvement has been consistently demonstrated since the beginning of the outbreak. Gastrointestinal manifestations in COVID-19 may be explained by the abundant expression of ACE2 in the digestive tract. Moreover, not only COVID-19 patients often present with GI symptoms (diarrhea, nausea/vomiting, abdominal pain) and liver tests abnormalities, but there are also data showing active viral replication in the GI tract and possible fecal-oral transmission. Aim of this review is to summarize the evidence regarding prevalence and clinical significance of GI involvement and liver abnormalities in patients with COVID-19, providing the reader with evidence-based recommendations on the management of these conditions.

Indexed as

COVID-19DiarrheaDigestiveGastrointestinalHepatitisLiver injurySymptoms

Identifiers

PMID33521703
PMCPMC7825983
OpenAlexW3124032887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.