Evidence map›Paper›PMID 33521701›Full record

ArticleCell reports. Medicine2021

Pulmonary MTBVAC vaccination induces immune signatures previously correlated with prevention of tuberculosis infection.

Karin Dijkman, Nacho Aguilo, Charelle Boot, Sam O Hofman, Claudia C Sombroek, Richard A W Vervenne, Clemens H M Kocken, Dessislava Marinova, Jelle Thole, Esteban Rodríguez and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports. Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Drug resistance mechanisms inFrontiers in pharmacology · 2026
    Review
  5. Article
  6. bioRxiv : the preprint server for biology · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Antigen specificity shapes antibody functions in tuberculosis.bioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Low-doseFrontiers in immunology · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Karin DijkmanBiomedical Primate Research Centre (BPRC), Rijswijk, the Netherlands.
Nacho AguiloDepartment of Microbiology, Faculty of Medicine, IIS Aragon, University of Zaragoza, Zaragoza, Spain.
Charelle BootBiomedical Primate Research Centre (BPRC), Rijswijk, the Netherlands.
Sam O HofmanBiomedical Primate Research Centre (BPRC), Rijswijk, the Netherlands.
Claudia C SombroekBiomedical Primate Research Centre (BPRC), Rijswijk, the Netherlands.
Richard A W VervenneBiomedical Primate Research Centre (BPRC), Rijswijk, the Netherlands.
Clemens H M KockenBiomedical Primate Research Centre (BPRC), Rijswijk, the Netherlands.
Dessislava MarinovaDepartment of Microbiology, Faculty of Medicine, IIS Aragon, University of Zaragoza, Zaragoza, Spain.
Jelle TholeTuBerculosis Vaccine Initiative (TBVI), Lelystad, the Netherlands.
Esteban RodríguezBiofabri, Pontevedra, Spain.
Michel P M VierboomBiomedical Primate Research Centre (BPRC), Rijswijk, the Netherlands.
Krista G HaanstraBiomedical Primate Research Centre (BPRC), Rijswijk, the Netherlands.
Eugenia PuentesBiofabri, Pontevedra, Spain.
Carlos MartinDepartment of Microbiology, Faculty of Medicine, IIS Aragon, University of Zaragoza, Zaragoza, Spain.
Frank A W VerreckBiomedical Primate Research Centre (BPRC), Rijswijk, the Netherlands.
Biomedical Primate Research Centre · NLUniversidad de Zaragoza · ESTuBerculosis Vaccine Initiative · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To fight tuberculosis, better vaccination strategies are needed. Live attenuated

Indexed as

Immunity, MucosalAdministration, IntranasalAnimalsBCG VaccineCellular ReprogrammingFemaleGene Expression RegulationInjections, IntradermalInterleukin-10Interleukin-17LungMacaca mulattaMaleMonocytesMycobacterium tuberculosisRespiratory MucosaBCG VaccineIl17a protein, mouseInterleukin-10Interleukin-17MTBVAC vaccineTuberculosis VaccinesTumor Necrosis Factor-alphaantibodiesBCGimmune correlatesMTBVACmucosal immunitynon-human primateTh1/Th17tissue-resident memorytuberculosisvaccination

Identifiers

PMID33521701
PMCPMC7817873
OpenAlexW3123483424

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.