Evidence map›Paper›PMID 33521647›Full record

ArticleCritical care explorations2021

Dysphagia in Patients With Severe Coronavirus Disease 2019-Potential Neurologic Etiologies.

Rainer Dziewas, Lisa-Marie Hufelschulte, Johannes Lepper, Jan Sackarnd, Jens Minnerup, Inga Teismann, Sigrid Ahring, Inga Claus, Bendix Labeit, Paul Muhle and 3 more

Open access · goldAbstract read
In one paragraph

Article in Critical care explorations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Guideline
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  3. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Rainer DziewasDepartment of Neurology, University Hospital Münster, 48149 Münster, Germany.
Lisa-Marie HufelschulteDepartment of Neurology, University Hospital Münster, 48149 Münster, Germany.
Johannes LepperDepartment of Cardiology, University Hospital Münster, 48149 Münster, Germany.
Jan SackarndDepartment of Cardiology, University Hospital Münster, 48149 Münster, Germany.
Jens MinnerupDepartment of Neurology, University Hospital Münster, 48149 Münster, Germany.
Inga TeismannDepartment for Stroke and Respiratory Medicine, Alexianer Misericordia GmbH, Düesbergweg 124, 48153 Münster, Germany.
Sigrid AhringDepartment of Neurology, University Hospital Münster, 48149 Münster, Germany.
Inga ClausDepartment of Neurology, University Hospital Münster, 48149 Münster, Germany.
Bendix LabeitDepartment of Neurology, University Hospital Münster, 48149 Münster, Germany.
Paul MuhleDepartment of Neurology, University Hospital Münster, 48149 Münster, Germany.
Sonja Suntrup-KrügerDepartment of Neurology, University Hospital Münster, 48149 Münster, Germany.
Tobias WarneckeDepartment of Neurology, University Hospital Münster, 48149 Münster, Germany.
Jan-Sören PadbergDepartment of Cardiology, University Hospital Münster, 48149 Münster, Germany.
University Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceDysphagia is a common complication of critical illness, and many known risk factors are also present in critically ill coronavirus disease 2019 victims.

objectivesTo investigate dysphagia in patients with severe coronavirus disease 2019. DESIGN SETTING AND

participantsIn this case series, we report results of dedicated evaluation of swallowing function in six consecutive, tracheotomized coronavirus disease 2019 patients after they had survived acute respiratory distress syndrome and were weaned from the respirator. MAIN OUTCOMES AND MEASURES: Dysphagia was assessed with flexible endoscopic evaluation of swallowing.

resultsThree patients suffered from severe dysphagia and airway compromise precluding decannulation, whereas in the other, three swallowing was less critically impaired, and the tracheal cannula could be removed. Four patients presented with additional laryngeal dysfunctions not typically seen in acute respiratory distress syndrome survivors. CONCLUSION AND RELEVANCE: Dysphagia with impaired airway protection is a key feature in coronavirus disease 2019 acute respiratory distress syndrome survivors. Apart from critical illness polyneuropathy, coronavirus disease 2019-related involvement of the peripheral and central nervous system may contribute to swallowing impairment and laryngeal dysfunction.

Indexed as

acute respiratory distress syndrome; coronavirus disease 2019; dysphagia; flexible endoscopic evaluation of swallowing; tracheostomy

Identifiers

PMID33521647
PMCPMC7837983
OpenAlexW3122552512

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.