Evidence map›Paper›PMID 33521638›Full record

ArticleNeuro-oncology advances2020

Multi-institutional noninvasive in vivo characterization of

Saima Rathore, Suyash Mohan, Spyridon Bakas, Chiharu Sako, Chaitra Badve, Sarthak Pati, Ashish Singh, Dimitrios Bounias, Phuc Ngo, Hamed Akbari and 11 more

Open access · goldAbstract read
In one paragraph

Article in Neuro-oncology advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Accuracy of Radiomics in PredictingRadiology. Artificial intelligence · 2024
    Pooled it
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  18. Optimization of Deep Learning Based Brain Extraction in MRI for Low Resource Environments.Brainlesion : glioma, multiple sclerosis, stroke and traumatic brain injuries. BrainLes (Workshop) · 2022
    Article
  19. Molecular Biology in Treatment Decision Processes-Neuro-Oncology Edition.International journal of molecular sciences · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 1 country.

Saima RathoreCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Suyash MohanDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Spyridon BakasCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Chiharu SakoCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Chaitra BadveDepartment of Radiology, University Hospitals Cleveland, Cleveland, Ohio, USA.
Sarthak PatiCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ashish SinghCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Dimitrios BouniasCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Phuc NgoCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Hamed AkbariCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Aimilia GastouniotiCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Mark BergmanCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Michel BilelloCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Russell T ShinoharaPenn Statistics in Imaging and Visualization Center (PennSIVE), Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Paul YushkevichPenn Image Computing and Science Lab (PICSL), University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Donald M O'RourkeGlioblastoma Translational Center of Excellence, Abramson Cancer Center, Philadelphia, Pennsylvania, USA.
Andrew E SloanCase Comprehensive Cancer Center, Cleveland, Ohio, USA.
Despina KontosCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
MacLean P NasrallahDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jill S Barnholtz-SloanCase Comprehensive Cancer Center, Cleveland, Ohio, USA.
Christos DavatzikosCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
University of Pennsylvania · USCase Western Reserve University · USAbramson Cancer CenterUniversity Hospitals of Cleveland · US

Funding

Statistical atlases of brain tumor MRI:do imaging phenotypes predict progression?R01NS042645 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2002 to 2024
$8.7M
Cancer imaging phenomics software suite: application to brain and breast cancerU24CA189523 · NCI · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS, KONTOS, DESPINA · 2015 to 2019
$3.2M
Biomedical Image Computing and Informatics ClusterS10OD023495 · OD · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2017 to 2017
$1.9M
NCI NIH HHS U24 CA189523NIH HHS S10 OD023495NINDS NIH HHS R01 NS042645
6 · The paper itself

Abstract

backgroundGliomas represent a biologically heterogeneous group of primary brain tumors with uncontrolled cellular proliferation and diffuse infiltration that renders them almost incurable, thereby leading to a grim prognosis. Recent comprehensive genomic profiling has greatly elucidated the molecular hallmarks of gliomas, including the mutations in

methodsWe developed a method for

resultsThese models achieved a classification accuracy of 86.74% (HUP), 85.45% (TCIA), and 75.15% (TCIA) in identifying EGFRvIII,

conclusionsUsing machine learning algorithms, high accuracy was achieved in the prediction of

Indexed as

gliomasmachine learningmolecular markersopen-source softwareradio(geno)mics

Identifiers

PMID33521638
PMCPMC7829474
OpenAlexW3125468979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.