ArticleBMJ nutrition, prevention & health2020
Perfluoroalkyl substances (PFASs) and mercury in never-pregnant women of fertile age: association with fish consumption and unfavorable lipid profile.
Article in BMJ nutrition, prevention & health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03272022 (Micronutrient Status in Pregnant and Lactating Women and Their Infants), which is not on this map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Micronutrient Status in Pregnant and Lactating Women and Their Infants
Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- Combined Effects of PFAS and Metals on Cognitive Function.Environments (Basel, Switzerland) · 2026Article
- Associations Between Seafood Consumption and Serum PFAS Levels Among Asian/Pacific Islanders in the San Francisco Bay Area, California.Exposure and health · 2026Article
- Environmental behavior and human health risks of PFAS: occurrence, toxicity, and the state-of-the-art removal approaches.RSC advances · 2025Review
- Associations of per- and polyfluoroalkyl substances and heavy metals with blood lipid profiles in a representative sample of Korean adolescents.Environmental health : a global access science source · 2024Article
- Prenatal per- and polyfluoroalkyl substances (PFAS) and maternal oxidative stress: Evidence from the LIFECODES study.Chemosphere · 2024Article
- Systematic evidence mapping of potential correlates of exposure for per- and poly-fluoroalkyl substances (PFAS) based on measured occurrence in biomatrices and surveys of dietary consumption and product use.International journal of hygiene and environmental health · 2024Review
- Associations of per- and polyfluoroalkyl substances with maternal metabolic and inflammatory biomarkers in early-to-mid-pregnancy.Environmental research · 2024Article
- Associations of per- and polyfluoroalkyl substances with maternal early second trimester sex-steroid hormones.International journal of hygiene and environmental health · 2024Article
- Characterizing Important Dietary Exposure Sources of Perfluoroalkyl Acids in Inuit Youth and Adults in Nunavik Using a Feature Selection Tool.Environmental health perspectives · 2024Article
- A review of cardiovascular effects and underlying mechanisms of legacy and emerging per- and polyfluoroalkyl substances (PFAS).Archives of toxicology · 2023Review
- Association between fish oil supplements use and serum per- and polyfluoroalkyl substances (PFAS): Results from the National Health and Nutrition Examination Survey.Environmental research · 2022Article
- Article
- Per- and Polyfluoroalkyl Substances and Risk of Myocardial Infarction and Stroke: A Nested Case-Control Study in Sweden.Environmental health perspectives · 2022Article
- Comprehensive Review Regarding Mercury Poisoning and Its Complex Involvement in Alzheimer's Disease.International journal of molecular sciences · 2022Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo examine concentrations of perfluoroalkyl substances (PFASs) and lifestyle factors that may contribute to higher levels of pollutants in never-pregnant women of fertile age.
designObservational cross-sectional study.
settingParticipants were recruited among employees and students at Haukeland University Hospital and the University of Bergen, Norway.
participantsHealthy, never-pregnant Norwegian women (n=158) of fertile age (18-39 years). OUTCOMES: Concentrations of 20 different PFASs, mercury (Hg), lead, cadmium, total, high-density lipoprotein and low-density lipoprotein (LDL) cholesterol, in addition to self-reported data on dietary intake.
resultsSeven PFASs were detected in more than 95% of the women. Women aged 30-39 years had higher concentrations of sum PFAS compared with younger women. Serum PFASs were significantly intercorrelated (rho: 0.34-0.98, p<0.001) and six of them were significantly correlated to whole blood Hg (rho: 0.21-0.74, p<0.01). Fish consumption was the strongest predictor for most serum PFASs and for whole blood Hg. Fish consumption and serum perfluorooctanesulfonic acid (PFOS) concentrations were both positively associated with serum total and LDL cholesterol, established risk factors for cardiovascular disease.
conclusionsThe majority of Norwegian never-pregnant women of fertile age had a mixture of seven different PFASs and Hg detected in their blood. PFAS concentrations were higher in older women and associated with fish intake. As the mean age of women at first birth is increasing, several factors require further consideration including diet, as this may influence the burden of PFAS to the next generation. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov ID: NCT03272022, Unique Protocol ID: 2011/2447, Regional Committee for Medical Research Ethics West (2011/2447), 12 January 2012.
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