Trial reportPain reports
Clinical outcome assessment in clinical trials of chronic pain treatments.
Trial report in Pain reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 53 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Examining Different Components of Online Acceptance and Commitment Therapy for Chronic Pain in a Sample of People With Chiari Malformation
A Modular Open Label, Signal Seeking, Phase II Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations (TARGET-VM)
A Prospective, Open-label Self-controlled Trial to Assess Long-term Changes in Pain and Function with Addition of 5% Dextrose to Local Anesthetic Solutions - the PALPADE Study
Who cites it
53 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Chronic postsurgical pain following thyroidectomy: A systematic review and meta-analysis.Medicine · 2026Pooled it
- The Effect of Corticosteroid Doses on Pain in Knee Osteoarthritis: A Systematic Review and Meta-Analysis.Musculoskeletal care · 2025Pooled it
- Systematic literature review of the humanistic and economic burden of focal epilepsy and primary generalized tonic-clonic seizures in adults.Epilepsia open · 2024Pooled it
- Physical activity and pain in people with cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Pooled it
- Assessing chemotherapy-induced peripheral neuropathy with patient reported outcome measures: a systematic review of measurement properties and considerations for future use.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Pooled it
- Efficacy of interventions to reduce long term opioid treatment for chronic non-cancer pain: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2022Pooled it
- Digital Acceptance and Commitment Therapy for the Treatment of Chronic Pain: Findings of a Randomized Controlled Efficacy Trial.Deutsches Arzteblatt international · 2026Trial
- Detecting Feigned Pain Using an Eye-Tracker Integrated Numerical Pain Rating Scale (NPRS).Pain practice : the official journal of World Institute of Pain · 2025Trial
- Motor cortex repetitive transcranial magnetic stimulation in fibromyalgia: a multicentre randomised controlled trial.British journal of anaesthesia · 2025Trial
- A secondary analysis of how changes in pain interference relate to changes in health-related quality of life and physical function in heart failure.Heart & lung : the journal of critical careTrial
- The ACTTION Guide to Clinical Trials of Pain Treatments, part II: mitigating bias, maximizing value.Pain reportsTrial
- Trial
- Development of a core outcome set for clinical trials of extended reality for pain.Pain reports · 2026Article
- Predicting pain outcomes after digital care in chronic spinal pain: the roles of disability, work impairment, and occupation in a secondary analysis of a prospective clinical study.Pain medicine (Malden, Mass.) · 2026Observational
- Feasibility and Preliminary Efficacy of Empowered Relief in Patients With Chronic Pain Taking Methadone or Buprenorphine: Single-Arm National Pilot Study.JMIR formative research · 2026Article
- Psychological mediators in chronic spinal pain after fully remote digital rehabilitation: a real-world, large-sample study.Physical therapy · 2026Article
- Development and Validation of the Brief Inventory of Treatment Expectations in Chronic Pain (BITEC).European journal of pain (London, England) · 2026Article
- Electrical muscle stimulation towards self-physiotherapy on myofascial pain syndrome.Frontiers in rehabilitation sciences · 2026Article
- Exploring the Impact of Behavioral Engagement Indicators on Pain Outcomes in AI-Enabled Musculoskeletal Rehabilitation: A Real-World Investigation.Journal of pain research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clinical outcome assessments (COAs) measure outcomes that are meaningful to patients in clinical trials and are critical for determining whether a treatment is effective. The objectives of this study are to (1) describe the different types of COAs and provide an overview of key considerations for evaluating COAs, (2) review COAs and other outcome measures for chronic pain treatments that are recommended by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) or other expert groups, and (3) review advances in understanding pain-related COAs that are relevant to clinical trials. The authors reviewed relevant articles, chapters, and guidance documents from the European Medicines Agency and U.S. Food and Drug Administration. Since the original core set of outcome measures were recommended by IMMPACT 14 years ago, several new advancements and publications relevant to the measurement or interpretation of COAs for chronic pain trials have emerged, presenting new research opportunities. Despite progress in the quality of measurement of several outcome domains for clinical trials of chronic pain, there remain some measurement challenges that require further methodological investigation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.