Evidence map›Paper›PMID 33521414›Full record

ArticleCurrent opinion in physiology2021

Chemical and electrical synaptic interactions among taste bud cells.

Stephen D Roper

Open access · greenAbstract read
In one paragraph

Article in Current opinion in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. The role of GABA in modulation of taste signaling within the taste bud.Pflugers Archiv : European journal of physiology · 2024
    Article
  4. Sweet Taste Signaling: The Core Pathways and Regulatory Mechanisms.International journal of molecular sciences · 2022
    Review
  5. Taste Bud Connectome: Implications for Taste Information Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  6. Review
  7. Encoding Taste: From Receptors to Perception.Handbook of experimental pharmacology · 2022
    Article
  8. The Role of ATP and Purinergic Receptors in Taste Signaling.Handbook of experimental pharmacology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Stephen D RoperDepartment of Physiology & Biophysics and Department of Otolaryngology, Miller School of Medicine, University of Miami, FL 33136.
University of Miami · US

Funding

SIGNALING IN TASTE CELLSR01DC006308 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CHAUDHARI, NIRUPA · 2005 to 2020
$4.9M
Research Supplement to Promote Diversity in Health-Related Research-Functions of gustatory afferent neuron types.R01DC018733 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CHAUDHARI, NIRUPA, ROPER, STEPHEN D. · 2020 to 2025
$3.3M
A new method to measure taste bud functionR01DC007630 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ROPER, STEPHEN D. · 2006 to 2016
$3.1M
Mapping gustatory neuron types.R01DC017303 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CHAUDHARI, NIRUPA · 2019 to 2023
$2.3M
Imaging Molecules and Circuits in Peripheral Taste PathwaysR01DC014420 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CHAUDHARI, NIRUPA, ROPER, STEPHEN D. · 2015 to 2019
$1.3M
NIDCD NIH HHS R01 DC006308NIDCD NIH HHS R01 DC007630NIDCD NIH HHS R01 DC014420NIDCD NIH HHS R01 DC017303NIDCD NIH HHS R01 DC018733
6 · The paper itself

Abstract

Chemical synapses between taste cells were first proposed based on electron microscopy of fish taste buds. Subsequently, researchers found considerable evidence for electrical coupling in fish, amphibian, and possibly mammalian taste buds. The development lingual slice and isolated cell preparations allowed detailed investigations of cell-cell interactions, both chemical and electrical, in taste buds. The identification of serotonin and ATP as taste neurotransmitters focused attention onto chemical synaptic interactions between taste cells and research on electrical coupling faded. Findings from Ca

Indexed as

ATPautocrinedye-couplingGABAgap junctionsneurotransmittersparacrineserotonin

Identifiers

PMID33521414
PMCPMC7843006
OpenAlexW3120080305

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.