ArticleInternational journal of cardiology. Heart & vasculature2021
Left ventricular global longitudinal strain in identifying subclinical myocardial dysfunction among patients hospitalized with COVID-19.
Article in International journal of cardiology. Heart & vasculature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Abnormal Echocardiographic Findings in Hospitalized Patients with Covid-19: A Systematic Review and Meta-analysis.Arquivos brasileiros de cardiologia · 2022Pooled it
- Echocardiographic assessment of the right ventricle in COVID-19: a systematic review.The international journal of cardiovascular imaging · 2021Pooled it
- Echocardiography, lung ultrasound, and cardiac magnetic resonance findings in COVID-19: A systematic review.Echocardiography (Mount Kisco, N.Y.) · 2021Pooled it
- The effect of hyperbaric oxygen therapy on myocardial function in post-COVID-19 syndrome patients: a randomized controlled trial.Scientific reports · 2023Trial
- COVID-19 is associated with cardiac structural and functional remodelling in healthy middle-aged and older individuals.Clinical physiology and functional imaging · 2025Observational
- Article
- Paucisymptomatic post COVID-19 myocarditis in a young athlete during return to play workflow: possible usefulness of global longitudinal strain analysis.BMJ case reports · 2024Article
- Spectrum of myocardial involvement in patients with COVID-19 - An echocardiography study.Journal of cardiovascular and thoracic research · 2024Article
- Cardiac Phenotyping of SARS-CoV-2 in British Columbia: A Prospective Echo Study With Strain Imaging.Journal of cardiovascular imaging · 2023Article
- Strain Echocardiography in Acute COVID-19 and Post-COVID Syndrome: More than Just a Snapshot.Biomedicines · 2023Review
- The usefulness of speckle tracking echocardiography in identifying subclinical myocardial dysfunction in young adults recovered from mild COVID-19.Echocardiography (Mount Kisco, N.Y.) · 2022Article
- Article
- Echocardiography in COVID-19 Pandemic: Clinical Findings and the Importance of Emerging Technology.Cardiac electrophysiology clinics · 2022Review
- Cardiovascular System during SARS-CoV-2 Infection.International journal of environmental research and public health · 2022Review
- Point of care echocardiography and lung ultrasound in critically ill patients with COVID-19.Wiener klinische Wochenschrift · 2021Article
- Acute and Chronic Effects of COVID-19 on the Cardiovascular System.Journal of cardiovascular development and disease · 2021Review
- Left ventricular global longitudinal strain in low cardiac risk outpatients who recently recovered from coronavirus disease 2019.The international journal of cardiovascular imaging · 2021Article
- Echocardiography in Coronavirus Disease 2019 Era: A Single Tool for Diagnosis and Prognosis.Journal of cardiovascular echographyReview
- Can Global Longitudinal Strain Assess Asymptomatic Subtle Left Ventricular Dysfunction in Recovered COVID-19 Patients?Journal of cardiovascular echographyArticle
- [Comparative analysis of myocardial deformation in patients recovered from mild SARS-CoV-2 infection].Archivos peruanos de cardiologia y cirugia cardiovascularArticle
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe incidence of acute cardiac injury in COVID-19 patients is very often subclinical and can be detected by cardiac magnetic resonance imaging. The aim of this study was to assess if subclinical myocardial dysfunction could be identified using left ventricular global longitudinal strain (LV-GLS) in patients hospitalized with COVID-19.
methodsWe performed a search of COVID-19 patients admitted to our institution from January 1st, 2020 to June 8th, 2020, which revealed 589 patients (mean age = 66 ± 18, male = 56%). All available 60 transthoracic echocardiograms (TTE) were reviewed and off-line assessment of LV-GLS was performed in 40 studies that had sufficient quality images and the views required to calculate LV-GLS. We also analyzed electrocardiograms and laboratory findings including inflammatory markers, Troponin-I, and B-type natriuretic peptide (BNP).
resultsOf 589 patients admitted with COVID-19 during our study period, 60 (10.1%) underwent TTE during hospitalization. Findings consistent with overt myocardial involvement included reduced ejection fraction (23%), wall motion abnormalities (22%), low stroke volume (82%) and increased LV wall thickness (45%). LV-GLS analysis was available for 40 patients and was abnormal in 32 patients (80%). All patients with LV dysfunction had elevated cardiac enzymes and positive inflammatory biomarkers.
conclusionsSubclinical myocardial dysfunction as measured via reduced LV-GLS is frequent, occurring in 80% of patients hospitalized with COVID-19, while prevalent LV function parameters such as reduced EF and wall motion abnormalities were less frequent findings. The mechanism of cardiac injury in COVID-19 infection is the subject of ongoing research.
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