ArticleEuropean journal of radiology open2021
Etiological profile and main imaging findings in patients with granulomatous diseases who underwent lung biopsy.
Article in European journal of radiology open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 13 citations in OpenAlex.
- Multiparametric Ultrasound Findings of Testicular Sarcoidosis.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026Article
- Radiological features of chronic pulmonary histoplasmosis: Easily mistaken for tuberculosis.PLoS neglected tropical diseases · 2025Review
- Exogenous lipoid pneumonia masquerading as a pulmonary nodule: a case report.Frontiers in medicine · 2025Article
- Noninfectious Granulomatous Lung Disease: Radiological Findings and Differential Diagnosis.Journal of personalized medicine · 2024Review
- Pulmonary Histoplasmosis in People Living with Human Immunodeficiency Virus in French Guiana: Clinical Epidemiology, Medical Imaging and Prognostic.Mycopathologia · 2023Article
- Potential Role of Intrapulmonary Concomitant Lesions in Differentiating Non-Neoplastic and Neoplastic Ground Glass Nodules.Journal of inflammation research · 2023Article
- Granulomatous lymphadenitis in the inferior pulmonary ligament.BJR case reports · 2022Article
- The adding value of contrast-enhanced CT radiomics: Differentiating tuberculosis from non-tuberculous infectious lesions presenting as solid pulmonary nodules or masses.Frontiers in public health · 2022Article
- Analysis of the Clinical Characteristics of Tuberculosis Patients based on Multi-Constrained Computed Tomography (CT) Image Segmentation Algorithm.Pakistan journal of medical sciences · 2021Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundGranulomatous Lung Diseases (GLD) encompasses a wide range of infectious and non-infectious conditions characterized by chronic inflammatory response. However, different GLD may share similar imaging findings. In this context, the purpose of this study was to outline the etiological profile and their imaging features in patients with GLD who underwent lung biopsy.
methodsPatients with granulomatous lesions in lung biopsies and previous chest CT performed from 2014 to 2017 at our institution had imaging data reviewed by three blinded radiologists. The imaging features were analyzed according to the Fleischner Society glossary. Categorical data were represented by absolute (n) and relative (%) frequency. The contingency matrices were analyzed by Pearson's Chi-square test. Interreader agreement was assessed by calculating the intraclass correlation coefficient, using kappa (κ) statistic.
resultsThirty-eight of 75 (50.7%) patients were women with a mean age of 59 ± 39 years. Infection was the most common cause of GLD (47/75, 62.7%) and
conclusionsIn our study population, the main etiologies found in patients with granulomatous disease who underwent lung biopsy were fungal or mycobacterial disease, specially histoplasmosis and tuberculosis, and nodular pattern with focal distribution was the most common imaging finding which was detected with substantial interreader agreement.
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