ArticleWorld journal of clinical cases2021
Effective immune-inflammation index for ulcerative colitis and activity assessments.
Article in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The predictive role of peripheral serum inflammatory markers NLR, PLR, and LMR in ulcerative colitis and Crohn's disease: a systematic review and meta-analysis.Frontiers in immunology · 2025Pooled it
- Abnormal platelet parameters in inflammatory bowel disease: a systematic review and meta-analysis.BMC gastroenterology · 2024Pooled it
- Association between the systemic immune-inflammation index and sarcopenia: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2024Pooled it
- The diagnostic role of the systemic inflammation index in patients with immunological diseases: a systematic review and meta-analysis.Clinical and experimental medicine · 2024Pooled it
- Endoscopic Activity Prediction in Ulcerative Colitis Using Hemogram-Derived Inflammatory Indices: Impact of Azathioprine Use on Diagnostic Performance.Journal of clinical medicine · 2026Article
- Diagnostic efficacy of pan-immune inflammation value for ulcerative colitis activity: a study based on multi-indicator comparison and diagnostic grey zone validation.BMC gastroenterology · 2026Article
- Inflammatory burden index (CRP×NLR) is associated with moderate-to-severe endoscopic activity in hospitalized patients with ulcerative colitis: a single-center retrospective study.Crohn's & colitis 360 · 2026Article
- Diagnostic Performance of Blood-Based Inflammatory Indices, Including a Novel Composite Score, for Estimating Fecal Calprotectin Levels in Pediatric Inflammatory Bowel Disease.Journal of clinical medicine · 2026Article
- Inflammatory, Nutritional, and Atherogenic Profiles Associated with Histologic Activity in Inflammatory Bowel Disease.Biomedicines · 2026Article
- Inflammation-related indices and low physical performance in older adults with unintentional weight loss: a cross-sectional study.BMC geriatrics · 2026Article
- Immune dysregulation driven by elevated platelet-to-lymphocyte ratio aggravates myasthenia gravis.The Journal of international medical research · 2026Article
- From tissue to blood: an integrated multi-omics signature identifies fibrogenesis and neutrophil activation as key drivers of ulcerative colitis severity.Frontiers in immunology · 2026Article
- Development of a Prediction Model for Combined Assessment of SII, Albumin, and Fibrinogen to Evaluate Frailty Risk in Patients with Inflammatory Bowel Disease.Journal of inflammation research · 2025Article
- Fermented mixed grain ameliorates chronic stress-induced depression-like behavior and memory deficit.Food science and biotechnology · 2024Article
- Clinical value of the Toronto inflammatory bowel disease global endoscopic reporting score in ulcerative colitis.World journal of gastroenterology · 2023Article
- Article
- The role of platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio in the diagnosis and severity of inflammatory bowel disease in children.European journal of pediatrics · 2023Article
- The systemic inflammation markers as possible indices for predicting respiratory failure and outcome in patients with myasthenia gravis.Annals of clinical and translational neurology · 2023Article
- Complete Blood Count-Derived Inflammatory Markers Changes in Dogs with Chronic Inflammatory Enteropathy Treated with Adipose-Derived Mesenchymal Stem Cells.Animals : an open access journal from MDPI · 2022Article
- Collagen peptide promotes DSS-induced colitis by disturbing gut microbiota and regulation of macrophage polarization.Frontiers in nutrition · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe inverse association between systemic immune-inflammation index (SII) and overall survival in tumors has been studied.
aimTo evaluate the hematological indexes for assessing the activity of ulcerative colitis (UC).
methodsIn this case-control study, 172 UC patients and healthy participants were included. Comparisons were made among groups of white blood cells, hemoglobin, platelets, neutrophils, lymphocytes, monocytes, SII, neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR). The relationship with hematological inflammation was verified by Spearman correlation analyses. The efficiency of SII, NLR, and PLR for distinguishing between UC and severe disease status was assessed by the receiver operator curve and logistic regression analyses.
resultsThe values of SII, NLR, and PLR were higher in UC patients than in controls (
conclusionSII has a certain value in confirming UC and identifying its activity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.