ReviewFrontiers in medicine2020
Association of Viral Infections With Oral Cavity Lesions: Role of SARS-CoV-2 Infection.
Review in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04821986 (Oral Manifestation in Patients With SARS-CoV2 Infection.), which is not on this map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Oral Manifestation in Patients With SARS-CoV2 Infection.
Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Oro-facial mucocutaneous manifestations of Coronavirus Disease-2019 (COVID-19): A systematic review.PloS one · 2022Pooled it
- Oral Manifestations of COVID-19 in Hospitalized Patients: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Oral Manifestations of COVID-19: Updated Systematic Review With Meta-Analysis.Frontiers in medicine · 2021Pooled it
- Oral and maxillofacial manifestations of COVID-19.GMS hygiene and infection control · 2026Review
- The Role of Saliva and Mouthwashes in the Detection and Reduction of Oral Viral Load: A Scoping Review.Viruses · 2025Article
- Oral hygiene influence on the incidence and severity of oral manifestations in Coronavirus Disease 2019.BMC oral health · 2025Article
- Obliteration of oral and maxillofacial region by SARS-CoV-2 infection.GMS hygiene and infection control · 2025Article
- Awareness of undergraduate dental students, interns, and freshly graduated dentists about oral manifestation associated with COVID-19.BMC oral health · 2023Article
- Host Transcriptional Regulatory Genes and Microbiome Networks Crosstalk through Immune Receptors Establishing Normal and Tumor Multiomics Metafirm of the Oral-Gut-Lung Axis.International journal of molecular sciences · 2023Review
- Biogeographical Impacts of Dental, Oral, and Craniofacial Microbial Reservoirs.Journal of dental research · 2023Review
- Identification of the causal relationship between sleep quality, insomnia, and oral ulcers.BMC oral health · 2023Article
- Depleting CD103+ resident memory T cells in vivo reveals immunostimulatory functions in oral mucosa.The Journal of experimental medicine · 2023Article
- Cetylpyridinium Chloride-Containing Mouthwashes Show Virucidal Activity against Herpes Simplex Virus Type 1.Viruses · 2023Article
- Psychological impact of COVID-19 Pandemic on dentists.African health sciences · 2023Review
- Antimicrobial activity of silver-copper coating against aerosols containing surrogate respiratory viruses and bacteria.PloS one · 2023Article
- Oral manifestations in hospital-admitted COVID-19 patients: a case control study.Frontiers in oral health · 2023Article
- Psychological impact of Covid-19 pandemic on dentists.African health sciences · 2022Review
- A case series of mucormycosis after covid infection in two hospitals.Journal of stomatology, oral and maxillofacial surgery · 2022Article
- Conservative treatment with mouthwashes followed by tongue photo biomodulation therapy in Covid-19: a case report.Journal of medical case reports · 2022Article
- Oral lesions and saliva alterations of COVID-19 patients in an intensive care unit: A retrospective study.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Different viral agents, such as herpesviruses, human papillomavirus, and Coxsackie virus, are responsible for primary oral lesions, while other viruses, such as human immunodeficiency virus, affect the oral cavity due to immune system weakness. Interestingly, it has been reported that coronavirus disease 2019 (COVID-19) patients can show cutaneous manifestations, including the oral cavity. However, the association between oral injuries and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is still unclear. This narrative review aimed to summarize the available literature and provide an overview of oral lesions associated with COVID-19. An online literature search was conducted to select relevant studies published up to November 2020. The results of 17 studies showed variability in oral lesions associated with COVID-19, including ulcerations, aphthous-like lesions, and macules. The tongue, lips, and palate were the most frequent anatomical locations. According to current knowledge, the etiopathogenesis of multiple COVID-19-associated lesions seems to be multifactorial. The appearance of such lesions could be related to the direct or indirect action of SARS-CoV-2 over the oral mucosa cells, coinfections, immunity impairment, and adverse drug reactions. Nevertheless, COVID-19-associated oral lesions may be underreported, mainly due to lockdown periods and the lack of mandatory dispositive protection. Consequently, further research is necessary to determine the diagnostic and pathological significance of oral manifestations of COVID-19. All medical doctors, dentists, and dermatologists are encouraged to perform an accurate and thorough oral examination of all suspected and confirmed COVID-19 cases to recognize the disease's possible early manifestations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.