ArticleScandinavian journal of child and adolescent psychiatry and psychology2018
Further evidence of high level of persistence of pediatric bipolar-I disorder from childhood onto young adulthood: a five-year follow up.
Article in Scandinavian journal of child and adolescent psychiatry and psychology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Findings from a pilot open-label trial of N-acetylcysteine for the treatment of pediatric mania and hypomania.BMC psychiatry · 2022Trial
- Long term outcomes of pediatric Bipolar-I disorder: A prospective follow-up analysis attending to full syndomatic, subsyndromal and functional types of remission.Journal of psychiatric research · 2022Article
- Higher socioeconomic status and less parental psychopathology improve prognosis in youths with bipolar disorder.Journal of affective disorders · 2022Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundPediatric bipolar (BP)-I disorder affects a sizeable minority of children and is associated with high levels of morbidity. Relatively few studies have assessed the persistence of the disorder over time.
objectiveThe main aim of this study was to extend our findings from our 4-year follow-up study examining rates of persistence of pediatric BP-I disorder onto late adolescent years and young adulthood 5 years after our original study.
methodsWe conducted a 1-year extension to our original prospective study of 78 youth, ages six to 17 years, with BP-I disorder at ascertainment, who were followed up into their adolescent and young adult years (14.9 ± 3.8). All subjects were comprehensively assessed with structured diagnostic interviews and psychosocial, educational, and treatment history assessments.
resultsOf the 78 BP-I participating youth, 68 were re-accessioned one year following the 4-year follow-up study, thus effectively 5 years since the original study. Of these, 63% continued to meet full (50%) or subthreshold (13%) diagnostic criteria for BP-I and 18% continued to have full or subthreshold major depressive disorder. Only 19% of BP-I youth were euthymic at the 5-year follow up. DISCUSSION: This 1-year extension study further documents the high level of persistence of pediatric BP-I from childhood onto late adolescence and young adulthood. The results provide compelling evidence of the morbidity and dysfunction associated with this disorder and its many forms. CLINICAL SIGNIFICANCE: This study adds to a small amount of literature on the persistence of pediatric BP disorder and the critical need for early identification and intervention.
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