Evidence map›Paper›PMID 33520681›Full record

ArticleWorld journal of orthopedics2021

Hallux rigidus treated with adipose-derived mesenchymal stem cells: A case report.

Adriano Braile, Giuseppe Toro, Annalisa De Cicco, Antonio Benedetto Cecere, Fabio Zanchini, Alfredo Schiavone Panni

Open access · diamondAbstract readCase Reports
In one paragraph

Article in World journal of orthopedics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Adriano BraileDepartment of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Naples 80138, Italy.
Giuseppe ToroDepartment of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Naples 80138, Italy. giusep.toro@gmail.com.
Annalisa De CiccoDepartment of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Naples 80138, Italy.
Antonio Benedetto CecereDepartment of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Naples 80138, Italy.
Fabio ZanchiniDepartment of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Naples 80138, Italy.
Alfredo Schiavone PanniDepartment of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Naples 80138, Italy.
University of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFirst metatarsophalangeal joint arthritis (FMTPA), also known as hallux rigidus, is the most frequent degenerative disease of the foot. Diagnosis is made through both clinical and radiological evaluation. Regenerative medicine showed promising results in the treatment of early osteoarthritis. The aim of the present study was to report the results of a case of FMTPA treated with the injection of autologous adipose-derived mesenchymal stem cells. CASE SUMMARY: A gentleman of 50 years of age presented with a painful hallux rigidus grade 2 resistant to any previous conservative treatment (including nonsteroidal anti-inflammatory drugs and hyaluronic acid injections). An injection of autologous adipose-derived mesenchymal stem cells into the first metatarsophalangeal joint was performed. No adverse events were reported, and both function and pain scales improved after 9 mo of follow-up.

conclusionThe FMTP joint injection of mesenchymal stem cells improved symptoms and function in our patient with FMTPA at 9 mo of follow-up.

Indexed as

Adipose derived-mesenchymal stem cellsCase reportEarly osteoarthritisFirst metatarsophalangeal joint arthritisHallux rigidusRegenerative medicineStem cells

Identifiers

PMID33520681
PMCPMC7814311
OpenAlexW3119598757

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.