Evidence map›Paper›PMID 33520452›Full record

ArticlePeerJ2021

Modeling the bidirectional glutamine/ammonium conversion between cancer cells and cancer-associated fibroblasts.

Peter Hinow, Gabriella Pinter, Wei Yan, Shizhen Emily Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Peter HinowDepartment of Mathematical Sciences, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.ORCID 0000-0001-5875-1470
Gabriella PinterDepartment of Mathematical Sciences, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
Wei YanDepartment of Pathology, University of California, San Diego, La Jolla, CA, USA.
Shizhen Emily WangDepartment of Pathology, University of California, San Diego, La Jolla, CA, USA.
University of California San Diego · USUniversity of Wisconsin–Milwaukee · US

Funding

Role of breast cancer-secreted miRNA in directing a stromal metabolic plasticityR01CA218140 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WANG, SHIZHEN EMILY · 2017 to 2021
$2.4M
NCI NIH HHS R01 CA218140
6 · The paper itself

Abstract

Like in an ecosystem, cancer and other cells residing in the tumor microenvironment engage in various modes of interactions to buffer the negative effects of environmental changes. One such change is the consumption of common nutrients (such as glutamine/Gln) and the consequent accumulation of toxic metabolic byproducts (such as ammonium/NH

Indexed as

Cancer-associated fibroblastsGlutamine/ammonium metabolismMathematical modeling

Identifiers

PMID33520452
PMCPMC7811294
OpenAlexW3119382235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.