Evidence map›Paper›PMID 33520390›Full record

ArticleBiomedical optics express2021

Multi-layer Shack-Hartmann wavefront sensing in the point source regime.

Vyas Akondi, Alfredo Dubra

Abstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Adaptive optics for high-resolution imaging.Nature reviews. Methods primers · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Vyas AkondiByers Eye Institute, Stanford University, Palo Alto, California 94303, USA.ORCID https://orcid.org/0000-0002-3987-2776
Alfredo DubraByers Eye Institute, Stanford University, Palo Alto, California 94303, USA.ORCID https://orcid.org/0000-0002-6506-9020

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
Platform Technologies for Microscopic Retinal Imaging: Development & TranslationU01EY025477 · NEI · STANFORD UNIVERSITY · PI DUBRA, ALFREDO · 2015 to 2019
$4.4M
Increasing the isoplanatic patch in adaptive optics ophthalmoscopyR01EY032147 · NEI · STANFORD UNIVERSITY · PI DUBRA, ALFREDO · 2021 to 2025
$2.4M
Improving rigor and reproducibility in adaptive optics ophthalmoscopyR01EY031360 · NEI · STANFORD UNIVERSITY · PI DUBRA, ALFREDO · 2020 to 2023
$2.3M
Axially-resolved Spectroscopic Ophthalmic ImagingR01EY025231 · NEI · STANFORD UNIVERSITY · PI DUBRA, ALFREDO · 2015 to 2019
$1.9M
Development, Validation and Application of Metabolic Imaging in GlaucomaR01EY028287 · NEI · STANFORD UNIVERSITY · PI DUBRA, ALFREDO, GOLDBERG, JEFFREY L · 2017 to 2019
$1.1M
NEI NIH HHS P30 EY026877NEI NIH HHS R01 EY025231NEI NIH HHS R01 EY028287NEI NIH HHS R01 EY031360NEI NIH HHS R01 EY032147NEI NIH HHS U01 EY025477
6 · The paper itself

Abstract

The Shack-Hartmann wavefront sensor (SHWS) is often operated under the assumption that the sensed light can be described by a single wavefront. In biological tissues and other multi-layered samples, secondary wavefronts from axially and/or transversely displaced regions can lead to artifactual aberrations. Here, we evaluate these artifactual aberrations in a simulated ophthalmic SHWS by modeling the beacons that would be generated by a two-layer retina in human and mouse eyes. Then, we propose formulae for calculating a minimum SHWS centroid integration area to mitigate these aberrations by an order of magnitude, potentially benefiting SHWS-based metrology and adaptive optics systems such as those used for retinal imaging and microscopy.

Identifiers

PMID33520390
PMCPMC7818966

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.