ArticleBiomedical optics express2021
Efficient and high accuracy 3-D OCT angiography motion correction in pathology.
Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Widefield OCT angiography.Progress in retinal and eye research · 2025Review
- Advances in OCT Angiography.Translational vision science & technology · 2025Review
- Rigid alignment method for secondary analyses of optical coherence tomography volumes.Biomedical optics express · 2024Article
- Perivenular Capillary Rarefaction in Diabetic Retinopathy: Interdevice Characterization and Association to Clinical Staging.Ophthalmology science · 2023Article
- Optical coherence tomography angiography for quantitative microvascular assessment in diabetic retinopathy: inter-device and intra-device agreement and correlation with clinical staging.Acta diabetologica · 2022Article
- Higher-order regression three-dimensional motion-compensation method for real-time optical coherence tomography volumetric imaging of the cornea.Journal of biomedical optics · 2022Article
- The Development and Clinical Application of Innovative Optical Ophthalmic Imaging Techniques.Frontiers in medicine · 2022Review
- Maximum a posteriori signal recovery for optical coherence tomography angiography image generation and denoising.Biomedical optics express · 2021Article
- OCT-OCTA segmentation: combining structural and blood flow information to segment Bruch's membrane.Biomedical optics express · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
We describe a novel method for non-rigid 3-D motion correction of orthogonally raster-scanned optical coherence tomography angiography volumes. This is the first approach that aligns predominantly axial structural features such as retinal layers as well as transverse angiographic vascular features in a joint optimization. Combined with orthogonal scanning and favorization of kinematically more plausible displacements, subpixel alignment and micrometer-scale distortion correction is achieved in all 3 dimensions. As no specific structures are segmented, the method is by design robust to pathologic changes. Furthermore, the method is designed for highly parallel implementation and short runtime, allowing its integration into clinical workflow even for high density or wide-field scans. We evaluated the algorithm with metrics related to clinically relevant features in an extensive quantitative evaluation based on 204 volumetric scans of 17 subjects, including patients with diverse pathologies and healthy controls. Using this method, we achieve state-of-the-art axial motion correction and show significant advances in both transverse co-alignment and distortion correction, especially in the subgroup with pathology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.