Evidence map›Paper›PMID 33520314›Full record

ArticleCritical care research and practice2021

A Retrospective Analysis of Thromboembolic Phenomena in Mechanically Ventilated Patients with COVID-19.

Fahad Faqihi, Abdulrahman Alharthy, Abdullah Balhamar, Nasir Nasim, Khaled Alanezi, Feisal Alaklobi, Ziad A Memish, Mike Blaivas, Saleh A Alqahtani, Dimitrios Karakitsos

Open access · goldAbstract read
In one paragraph

Article in Critical care research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Fahad FaqihiCritical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Abdulrahman AlharthyCritical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Abdullah BalhamarCritical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Nasir NasimCritical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Khaled AlaneziKing Saud Medical City, Riyadh, Saudi Arabia.
Feisal AlaklobiKing Saud Medical City, Riyadh, Saudi Arabia.
Ziad A MemishResearch and Innovation Center, King Saud Medical City, Riyadh, Saudi Arabia.
Mike BlaivasDepartment of Internal Medicine, University of South Carolina, School of Medicine, Columbia, SC, USA.
Saleh A AlqahtaniTransplant Hepatology Division of Gastroenterology and Hepatology, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.
Dimitrios KarakitsosCritical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0003-3370-7099
King Saud Medical City · SAUniversity of South Carolina · USJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies have shown an increased prevalence of thromboembolic disease in critically ill patients with the novel SARS-CoV-2 disease (COVID-19). However, the use of enhanced anticoagulation therapy in these patients remains controversial.

objectivesTo determine the incidence of thromboembolic phenomena (TEP) and hemorrhagic events (HEs) in intensive care unit (ICU) COVID-19 patients.

methodsOne hundred and sixty ICU patients with COVID-19 were enrolled. Clinical examination results, laboratory data, and imaging studies (computed tomography/Doppler ultrasound scans) for these patients were retrospectively collected and analyzed. Outcome measures including days on mechanical ventilation, ICU length of stay, and day-28 mortality were recorded.

resultsSixty patients (37.5%) developed TEP including thirty patients with deep vein thrombosis, 55 patients with pulmonary embolism, and 7 patients with arterial thromboembolism. Cardiac arrhythmias, lymphocytopenia, and increased D-dimers were more frequently observed in the TEP group compared to the non-TEP group of patients (all

conclusionsThe rates of TEP and HEs in mechanically ventilated critically ill COVID-19 patients were 37. 5% and 8.1%. Twenty-eight-day mortality was higher in the TEP group (60%) compared to the non-TEP group (30%) of patients.

Identifiers

PMID33520314
PMCPMC7805521
OpenAlexW3119456075

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.