Evidence map›Paper›PMID 33520127›Full record

ArticleJournal of ophthalmic & vision research

Prognostic Factors Associated with Ocriplasmin Efficacy for the Treatment of Symptomatic Vitreomacular Adhesion and Full-thickness Macular Hole: Analysis from Four Studies.

Brian C Joondeph, Paul Willems, Thomas Raber, Luc Duchateau, Joseph Markoff

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmic & vision research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Brian C JoondephColorado Retina Associates, Denver, Colorado, USA.
Paul WillemsOxurion, Leuven, Belgium.
Thomas RaberOxurion, Leuven, Belgium.
Luc DuchateauBiometrics Research Group, Ghent University, Gent, Belgium.
Joseph MarkoffWills Eye Hospital, Philadelphia, Pennsylvania, USA.
Oxurion (Belgium) · BEColorado Retina Center · USGhent University · BEJefferson College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the effect of patient baseline characteristics on the efficacy of ocriplasmin treatment for symptomatic vitreomacular adhesion (VMA) with full-thickness macular hole (FTMH) from phase 3/4 studies.

methodsPatients with symptomatic VMA and FTMH at baseline and receiving ocriplasmin treatment 125

resultsTwo hundred and seventy-four patients receiving ocriplasmin treatment were assessed. Overall, 22.6% (62/274) of the patients experienced both VMA resolution by Day 28 and non-surgical FTMH closure by Month 6. Patients with FTMH

conclusionThe analysis revealed that FMTH

Indexed as

Full-thickness Macular HoleOcriplasminSymptomatic Vitreomacular AdhesionVitreomacular AdhesionVitreomacular TractionVitreoretinal Interface

Identifiers

PMID33520127
PMCPMC7841271
OpenAlexW3125935911

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.