ArticleFrontiers in immunology2020
Arginase 1 Insufficiency Precipitates Amyloid-
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Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
What it found
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Who cites it
16 citing papers in PubMed, 25 citations in OpenAlex.
- ARG1-polyamine axis: cell-type-specific functions in disease pathogenesis and therapeutic targeting.Frontiers in immunology · 2026Review
- LimROTS: a hybrid method integrating empirical Bayes and reproducibility-optimized statistics for robust differential expression analysis.Bioinformatics (Oxford, England) · 2025Article
- Nutrient sensing receptor GPRC6A regulates mTORC1 signaling and Tau biology.Neurobiology of disease · 2025Article
- Haploinsufficiency and Alzheimer's Disease: The Possible Pathogenic and Protective Genetic Factors.International journal of molecular sciences · 2024Review
- Effects of the nerve agent VX on hiPSC-derived motor neurons.Archives of toxicology · 2024Article
- Regulated Arginine Metabolism in Immunopathogenesis of a Wide Range of Diseases: Is There a Way to Pass between Scylla and Charybdis?Current issues in molecular biology · 2023Review
- Article
- Metabolomic alterations in the blood plasma of older adults with mild cognitive impairment and Alzheimer's disease (from the Nakayama Study).Scientific reports · 2022Article
- Intrathecal Injection of the Secretome from ALS Motor Neurons Regulated for miR-124 Expression Prevents Disease Outcomes in SOD1-G93A Mice.Biomedicines · 2022Article
- Muramyl Dipeptide Administration Delays Alzheimer's Disease Physiopathology via NOD2 Receptors.Cells · 2022Article
- Stroke-Induced Neurological Dysfunction in Aged Mice Is Attenuated by Preconditioning with Young Sca-1+ Stem Cells.Stem cells (Dayton, Ohio) · 2022Article
- Lysophosphatidylcholine Alleviates Acute Lung Injury by Regulating Neutrophil Motility and Neutrophil Extracellular Trap Formation.Frontiers in cell and developmental biology · 2022Article
- Beyond the GFAP-Astrocyte Protein Markers in the Brain.Biomolecules · 2021Review
- Review
- Review
- Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-β Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer's Disease: A Targeted Transcriptome Analysis.Frontiers in immunology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 5 institutions in 1 country.
Chao MaDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Jerry B HuntSanders-Brown Center on Aging, Department of Neuroscience, College of Medicine, University of Kentucky, Lexington, KY, United States.
Maj-Linda B SelenicaDepartment of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, United States.
Awa SannehDepartment of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, United States.
Leslie A Sandusky-BeltranDepartment of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, United States.
Mallory WatlerDepartment of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, United States.
Rana DaasDepartment of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, United States.
Andrii KovalenkoDepartment of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, United States.
Huimin LiangSanders-Brown Center on Aging, Department of Neuroscience, College of Medicine, University of Kentucky, Lexington, KY, United States.
Devon PlacidesDepartment of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, United States.
Chuanhai CaoDepartment of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, United States.
Xiaoyang LinDepartment of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, United States.
Michael B OrrSpinal Cord and Brain Injury Research Center, Department of Physiology, College of Medicine, University of Kentucky, Lexington, KY, United States.
Bei ZhangSpinal Cord and Brain Injury Research Center, Department of Physiology, College of Medicine, University of Kentucky, Lexington, KY, United States.
John C GenselSpinal Cord and Brain Injury Research Center, Department of Physiology, College of Medicine, University of Kentucky, Lexington, KY, United States.
David J FeolaDepartment of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, KY, United States.
Marcia N GordonDepartment of Translational Neuroscience, College of Human Medicine, Michigan State University, Grand Rapids, MI, United States.
Dave MorganDepartment of Translational Neuroscience, College of Human Medicine, Michigan State University, Grand Rapids, MI, United States.
Paula C BickfordDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Daniel C LeeSanders-Brown Center on Aging, Department of Neuroscience, College of Medicine, University of Kentucky, Lexington, KY, United States.
University of South Florida · USUniversity of Kentucky · USMichigan State University · USCornell University · USJames A. Haley Veterans' Hospital · US
Funding
Influence of systemic immune inflammation upon the tauopathy phenotype in mouse modelsR01AG051500 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI MORGAN, DAVID · 2016 to 2020
$3.5MEmerging Roles of Higher-order Polyamines During TauopathiesR01AG054559 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI LEE, DANIEL CARL · 2017 to 2021
$2.4MAlternative macrophage activation in acute Pseudomonas pneumoniaR01AI095307 · NIAID · UNIVERSITY OF KENTUCKY · PI FEOLA, DAVID · 2012 to 2016
$1.8MThe role of macrophage phenotype and age in spinal cord injuryR01NS091582 · NINDS · UNIVERSITY OF KENTUCKY · PI GENSEL, JOHN C · 2015 to 2019
$1.6MUnderstanding the Role GPRC6a During Tau MetabolismR21AG055996 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI LEE, DANIEL CARL · 2018 to 2019
$411kAcomys as a Novel Mammalian Model of Spinal Cord InjuryF31NS110264 · NINDS · UNIVERSITY OF KENTUCKY · PI ORR, MICHAEL · 2019 to 2019
$35kBLRD Research Career Scientist Award ApplicationIK6BX004214 · VA · JAMES A. HALEY VA MEDICAL CENTER · PI BICKFORD, PAULA C · 2018 to 2025
–BLRD VA IK6 BX004214NIAID NIH HHS R01 AI095307NIA NIH HHS R01 AG051500NIA NIH HHS R01 AG054559NIA NIH HHS R21 AG055996NINDS NIH HHS F31 NS110264NINDS NIH HHS R01 NS091582
Abstract
Alzheimer's disease (AD) includes several hallmarks comprised of amyloid-
Indexed as
Amyloid beta-PeptidesAmyloidosisAnimalsArginaseAttention Deficit and Disruptive Behavior DisordersAutophagyBehavior, AnimalDisease Models, AnimalHumansMechanistic Target of Rapamycin Complex 1MiceMice, TransgenicMyeloid CellsNeurogenic InflammationSignal TransductionAmyloid beta-PeptidesArg1 protein, mouseArginaseMechanistic Target of Rapamycin Complex 1Alzheimer’s diseasearginine metabolismcognitionmacrophagemicroglianeuroinflammationphagocytosisTg2576
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.