Evidence map›Paper›PMID 33519804›Full record

ArticleFrontiers in immunology2020

A Population of Radio-Resistant Macrophages in the Deep Myenteric Plexus Contributes to Postoperative Ileus

Jana Enderes, Shilpashree Mallesh, Reiner Schneider, Kristof J Hupa, Mariola Lysson, Bianca Schneiker, Kristian Händler, Balthasar Schlotmann, Patrick Günther, Joachim L Schultze and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Jana EnderesDepartment of Surgery, Division of Immune Pathophysiology, University Hospital Bonn, Bonn, Germany.
Shilpashree MalleshDepartment of Surgery, Division of Immune Pathophysiology, University Hospital Bonn, Bonn, Germany.
Reiner SchneiderDepartment of Surgery, Division of Immune Pathophysiology, University Hospital Bonn, Bonn, Germany.
Kristof J HupaDepartment of Surgery, Division of Immune Pathophysiology, University Hospital Bonn, Bonn, Germany.
Mariola LyssonDepartment of Surgery, Division of Immune Pathophysiology, University Hospital Bonn, Bonn, Germany.
Bianca SchneikerDepartment of Surgery, Division of Immune Pathophysiology, University Hospital Bonn, Bonn, Germany.
Kristian HändlerPRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases (DZNE), University of Bonn, Bonn, Germany.
Balthasar SchlotmannGenomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
Patrick GüntherPRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases (DZNE), University of Bonn, Bonn, Germany.
Joachim L SchultzePRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases (DZNE), University of Bonn, Bonn, Germany.
Jörg C KalffDepartment of Surgery, Division of Immune Pathophysiology, University Hospital Bonn, Bonn, Germany.
Sven WehnerDepartment of Surgery, Division of Immune Pathophysiology, University Hospital Bonn, Bonn, Germany.
University Hospital Bonn · DEGerman Center for Neurodegenerative Diseases · DEUniversity of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative ileus (POI) is triggered by an innate immune response in the muscularis externa (ME) and is accompanied by bacterial translocation. Bacteria can trigger an innate immune response

Indexed as

Adaptor Proteins, Vesicular TransportAnimalsCX3C Chemokine Receptor 1Disease Models, AnimalFemaleGene ExpressionIleusImmunity, InnateMacrophagesMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicMyenteric PlexusPostoperative ComplicationsRadiation ToleranceAdaptor Proteins, Vesicular TransportCX3C Chemokine Receptor 1Cx3cr1 protein, mouseIfnar1 protein, mouseReceptor, Interferon alpha-betaTicam1 protein, mouseTLR3 protein, mouseToll-Like Receptor 3innate immune responsemacrophagespostoperative ileusTLR3TRIF

Identifiers

PMID33519804
PMCPMC7838642
OpenAlexW3120999330

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.