Evidence map›Paper›PMID 33519716›Full record

ArticleFrontiers in endocrinology2020

Immune System Effects of Insulin-Like Peptide 5 in a Mouse Model.

Brett Vahkal, Sergey Yegorov, Chukwunonso Onyilagha, Jacqueline Donner, Dean Reddick, Anuraag Shrivastav, Jude Uzonna, Sara V Good

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Brett VahkalDepartment of Biology, University of Winnipeg, Winnipeg, MB, Canada.
Sergey YegorovDepartment of Biology, University of Winnipeg, Winnipeg, MB, Canada.
Chukwunonso OnyilaghaDepartment of Immunology, University of Manitoba, Winnipeg, MB, Canada.
Jacqueline DonnerDepartment of Biology, University of Winnipeg, Winnipeg, MB, Canada.
Dean ReddickDepartment of Biology, University of Winnipeg, Winnipeg, MB, Canada.
Anuraag ShrivastavDepartment of Biology, University of Winnipeg, Winnipeg, MB, Canada.
Jude UzonnaDepartment of Immunology, University of Manitoba, Winnipeg, MB, Canada.
Sara V GoodDepartment of Biology, University of Winnipeg, Winnipeg, MB, Canada.
University of Winnipeg · CAUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Insulin-like peptide 5 (INSL5) is a peptide hormone with proposed actions in glucose homeostasis and appetite regulation Methods: Results: We find Conclusion: We propose that INSL5-RXFP4 play a novel role in both central and peripheral immune cell signaling.

Indexed as

AnimalsHumansImmune System PhenomenaImmunity, CellularMacrophagesMaleMiceMice, Inbred C57BLPeptide HormonesInsl5 protein, mousePeptide Hormonesgut peptide hormoneimmune markersimmune systeminsulin-like peptide 5metabolic syndromerelaxin family peptide receptor 4

Identifiers

PMID33519716
PMCPMC7841425
OpenAlexW3120058085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.