Evidence map›Paper›PMID 33519694›Full record

ArticleFrontiers in neurology2020

Case Report: Microglia Composition and Immune Response in an Immunocompetent Patient With an Intracranial Syphilitic Gumma.

Qian Yu, Wei Li, Xiaohui Mo, Fei Tan, Lianjuan Yang

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Qian YuDepartment of Medical Mycology, Shanghai Dermatology Hospital, Shanghai, China.
Wei LiDepartment of Medical Cosmetology, Shanghai Dermatology Hospital, Shanghai, China.
Xiaohui MoDepartment of Dermatology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Fei TanDepartment of Science and Education, Shanghai Dermatology Hospital, Shanghai, China.
Lianjuan YangDepartment of Medical Mycology, Shanghai Dermatology Hospital, Shanghai, China.
Shanghai Stomatological Hospital · CNRenji Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pathogenesis of intracranial syphilitic gummas remains poorly understood. Microglia are generally considered to be the main cell type of the innate immune system in the brain. Determination of the composition of infiltrating microglia of patients with typical intracranial syphilitic gummas may contribute to the understanding of the pathological process. We report a case of an intracranial syphilitic gumma who presented with right upper limb weakness. The histological analysis showed the presence of

Indexed as

humoral immunityintracranial syphilitic gummaM2 microgliamicrogliaTreponema pallidum

Identifiers

PMID33519694
PMCPMC7838610
OpenAlexW3200570952

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.