Evidence map›Paper›PMID 33519501›Full record

ArticleFrontiers in physiology2020

High Throughput Sequencing of MicroRNA in Rainbow Trout Plasma, Mucus, and Surrounding Water Following Acute Stress.

Heather Ikert, Michael D J Lynch, Andrew C Doxey, John P Giesy, Mark R Servos, Barbara A Katzenback, Paul M Craig

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Heather IkertDepartment of Biology, University of Waterloo, Waterloo, ON, Canada.
Michael D J LynchDepartment of Biology, University of Waterloo, Waterloo, ON, Canada.
Andrew C DoxeyDepartment of Biology, University of Waterloo, Waterloo, ON, Canada.
John P GiesyDepartment of Veterinary Biomedical Sciences, Toxicology Centre, University of Saskatchewan, Saskatoon, SK, Canada.
Mark R ServosDepartment of Biology, University of Waterloo, Waterloo, ON, Canada.
Barbara A KatzenbackDepartment of Biology, University of Waterloo, Waterloo, ON, Canada.
Paul M CraigDepartment of Biology, University of Waterloo, Waterloo, ON, Canada.
University of Waterloo · CAUniversity of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circulating plasma microRNAs (miRNAs) are well established as biomarkers of several diseases in humans and have recently been used as indicators of environmental exposures in fish. However, the role of plasma miRNAs in regulating acute stress responses in fish is largely unknown. Tissue and plasma miRNAs have recently been associated with excreted miRNAs; however, external miRNAs have never been measured in fish. The objective of this study was to identify the altered plasma miRNAs in response to acute stress in rainbow trout (

Indexed as

acute stressblood plasmahigh throughput sequencingmicroRNAmucusnon-lethalOncorhynchus mykisswater

Identifiers

PMID33519501
PMCPMC7838646
OpenAlexW3118613411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.