Evidence map›Paper›PMID 33519382›Full record

ArticleFrontiers in cellular neuroscience2020

P2RX7 in Dopaminergic Neurons of Ventral Periaqueductal Gray Mediates HTWP Acupuncture-Induced Consciousness in Traumatic Brain Injury.

Huiling Tang, Siru Qin, Wei Li, Xuyi Chen, Luis Ulloa, Qiumei Zhu, Baohu Liu, Yinan Gong, Yadan Zhao, Songtao Wang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Traumatic brain injury-related ferroptosis: current perspectives.Journal of molecular medicine (Berlin, Germany) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Huiling TangAcupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Siru QinAcupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Wei LiAcupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Xuyi ChenDepartment of Neurosurgery, Characteristic Medical Center of Chinese People's Armed Police Force, Tianjin, China.
Luis UlloaDepartment of Anesthesiology, Center of Perioperative Organ Protection, Duke University Medical Center, Durham, NC, United States.
Qiumei ZhuLuoding Hospital of Traditional Chinese Medicine, Guangdong, China.
Baohu LiuDepartment of Rehabilitation, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Yinan GongAcupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Yadan ZhaoAcupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Songtao WangAcupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Shanshan LiAcupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Yongming GuoAcupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Zhifang XuAcupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Yi GuoAcupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Tianjin University of Traditional Chinese Medicine · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNChinese People's Armed Police Force Medical College Affiliated Hospital · CNDuke Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The induction of a coma by traumatic brain injury (TBI) is a crucial factor for poor clinical prognoses. We report that acupuncture at the hand 12

Indexed as

acupuncturedopaminehand 12 Jing-well pointsneural projectionP2RX7traumatic brain injuryventral periaqueductal gray

Identifiers

PMID33519382
PMCPMC7838360
OpenAlexW3119544248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.