Evidence map›Paper›PMID 33519139›Full record

ArticleWorld journal of gastroenterology2021

Circular RNA AKT3 governs malignant behaviors of esophageal cancer cells by sponging miR-17-5p.

Hong-Liang Zang, Fu-Jian Ji, Hai-Ying Ju, Xiao-Feng Tian

Open access · greenAbstract read
In one paragraph

Article in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Circular RNAs and Cancers.Advances in experimental medicine and biology · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Role of RhoC in cancer cell migration.Cancer cell international · 2021
    Review
  9. Review
  10. Circular RNAs With Efficacy in PreclinicalCancer genomics & proteomics
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hong-Liang ZangDepartment of Hepatobiliary and Pancreatic Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China.
Fu-Jian JiDepartment of Colorectal Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China.
Hai-Ying JuDepartment of Hematology, Jilin Province Blood Center, Changchun 130000, Jilin Province, China.
Xiao-Feng TianDepartment of Hepatobiliary and Pancreatic Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China. fengwykctut4210@163.com.
Union Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies have demonstrated that circular RNA AKT3 (circAKT3) plays a crucial role in regulating the malignant phenotypes of tumor cells. However, the potential effects of circAKT3 on esophageal cancer have not been investigated.

aimTo illuminate the role of circAKT3 in malignant behaviors of esophageal cancer cells and its underlying mechanism.

methodsClinical samples were collected to detect the expression of

results

conclusionCircAKT3 contributed to the malignant behaviors of esophageal cancer

Indexed as

Esophageal NeoplasmsMicroRNAsAnimalsCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticMiceProto-Oncogene Proteins c-aktRNA, CircularAKT3 protein, humanMicroRNAsProto-Oncogene Proteins c-aktRNA, CircularCircular RNA AKT3Esophageal cancerInvasionMigrationmiR-17-5pProliferation

Identifiers

PMID33519139
PMCPMC7814369
OpenAlexW3120395686

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.