ReviewJournal of physical therapy science2021
An overview of fractional anisotropy as a reliable quantitative measurement for the corticospinal tract (CST) integrity in correlation with a Fugl-Meyer assessment in stroke rehabilitation.
Review in Journal of physical therapy science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- White matter lesions and DTI metrics related to various types of dysfunction in cerebral palsy: A meta-analysis and systematic review.PloS one · 2025Pooled it
- Transcutaneous electrical acupoint stimulation for upper limb spasticity after stroke: effect and feasibility-a randomised pilot study.BMJ supportive & palliative care · 2025Trial
- Article
- White Matter Structural Biomarkers Derived from Diffusion Tensor Imaging to Estimate Upper-Extremity Motor Function in Stroke Using Machine Learning.Brain topography · 2026Article
- Toward Precision Post-Stroke Rehabilitation Medicine: Integrating Molecular, Imaging, and Computational Biomarkers for Functional Outcome Prediction.Journal of clinical medicine · 2025Review
- Remodeling and Characterization Analysis of Corticospinal Tract in Patients with Intracerebral Hemorrhage in the Basal Ganglia.Translational stroke research · 2025Article
- The impact of brain network microstructural changes on upper limb mirror movements after stroke.Frontiers in neurology · 2025Article
- Early corticospinal tract sub-pathway lesion load and integrity predict post-stroke motor outcomes.Frontiers in human neuroscience · 2025Article
- Diffusion tensor imaging assessments to investigate motor impairment recovery after minor basal ganglia hemorrhage post-stereotactic surgery.Frontiers in neuroscience · 2025Article
- Motor mapping of the hand muscles using peripheral innervation-based navigated transcranial magnetic stimulation to identify functional reorganization of primary motor regions in malignant tumors.Human brain mapping · 2024Article
- Benefits of Robot-Assisted Upper-Limb Rehabilitation from the Subacute Stage after a Stroke of Varying Severity: A Multicenter Randomized Controlled Trial.Journal of clinical medicine · 2024Article
- Between neurons and networks: investigating mesoscale brain connectivity in neurological and psychiatric disorders.Frontiers in neuroscience · 2024Review
- Changes in Corticospinal Tract Consistency after Dry Needling in a Stroke Patient.Case reports in neurological medicine · 2024Article
- Assessment of bidirectional relationships between brain imaging-derived phenotypes and stroke: a Mendelian randomization study.BMC medicine · 2023Article
- Association between superior longitudinal fasciculus, motor recovery, and motor outcome after stroke: a cohort study.Frontiers in neurology · 2023Article
- Prognosis of the Ipsilesional Corticospinal Tracts with Preserved Integrities at the Early Stage of Cerebral Infarction: Follow Up Diffusion Tensor Tractography Study.Healthcare (Basel, Switzerland) · 2022Article
- Microstructure and Genetic Polymorphisms: Role in Motor Rehabilitation After Subcortical Stroke.Frontiers in aging neuroscience · 2022Review
- Effect of rTMS intervention on upper limb motor function after stroke: A study based on fNIRS.Frontiers in aging neuroscience · 2022Article
- Performance Comparison of Different Neuroimaging Methods for Predicting Upper Limb Motor Outcomes in Patients after Stroke.Neural plasticity · 2022Article
- Dynamic Relationship Between Interhemispheric Functional Connectivity and Corticospinal Tract Changing Pattern After Subcortical Stroke.Frontiers in aging neuroscience · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
[Purpose] Understanding the essential mechanisms in post-stroke recovery not only provides important basic insights into brain function and plasticity but can also guide the development of new therapeutic approaches for stroke patients. This review aims to give an overview of how various variables of Magnetic Resonance-Diffusion Tensor Imaging (MR-DTI) metrics of fractional anisotropy (FA) can be used as a reliable quantitative measurement and indicator of corticospinal tract (CST) changes, particularly in relation to functional motor outcome correlation with a Fugl-Meyer assessment in stroke rehabilitation. [Methods] PubMed electronic database was searched for the relevant literature, using key words of diffusion tensor imaging (dti), corticospinal tract, and stroke. [Results] We reviewed the role of FA in monitoring CST remodeling and its role of predicting motor recovery after stroke. We also discussed the mechanism of CST remodeling and its modulation from the value of FA and FMA-UE. [Conclusion] Heterogeneity of post-stroke brain disorganization and motor impairment is a recognized challenge in the development of accurate indicators of CST integrity. DTI-based FA measurements offer a reliable and evidence-based indicator for CST integrity that would aid in predicting motor recovery within the context of stroke rehabilitation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.