ArticleHorticulture research2021
Study of micro-trichome (mict) reveals novel connections between transcriptional regulation of multicellular trichome development and specific metabolism in cucumber.
Article in Horticulture research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Trichomes in Plant Defence, Development and Metabolic Integration Under Environmental Stress.Plant, cell & environment · 2026Review
- A Novel AP2/ERF Transcription Factor Controls Trichome Initiation and Fruit Development in Cucumber.Plant biotechnology journal · 2026Article
- Integration of Spatiotemporal Multi-Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome-Mediated Stress Adaptation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The role, regulation and application of plant fruit trichomes.Molecular horticulture · 2025Review
- Histological and Transcriptomic Insights into Rugose Surface Formation in Pepper (Plants (Basel, Switzerland) · 2025Article
- Glandless, a tomato HD-ZIP transcription factor, is important for the gland formation of type VI trichomes.The Plant journal : for cell and molecular biology · 2025Article
- CsTs, a C-type lectin receptor-like kinase, regulates the development trichome development and cuticle metabolism in cucumber (Horticulture research · 2024Article
- Novel players in organogenesis and flavonoid biosynthesis in cucumber glandular trichomes.Plant physiology · 2023Article
- Sequestration of cucurbitacins from cucumber plants byJournal of pest science · 2023Article
- CucumberHorticulture research · 2023Article
- Molecular Mechanisms of Plant Trichome Development.Frontiers in plant science · 2022Review
- Molecular research progress and improvement approach of fruit quality traits in cucumber.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Review
- Article
- A SNP of HD-ZIP I transcription factor leads to distortion of trichome morphology in cucumber (Cucumis sativus L.).BMC plant biology · 2021Article
- Advances in the Regulation of Epidermal Cell Development by C2H2 Zinc Finger Proteins in Plants.Frontiers in plant science · 2021Review
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
Abstract
Trichomes that cover the epidermis of aerial plant organs play multiple roles in plant protection. Compared with a unicellular trichome in model plants, the development mechanism of the multicellular trichome is largely unclear. Notably, variations in trichome development are often accompanied by defects in the biosynthesis of cuticle and secondary metabolites; however, major questions about the interactions between developmental differences in trichomes and defects in metabolic pathways remain unanswered. Here, we characterized the glabrous mutant mict/csgl1/cstbh via combined metabolomic and transcriptomic analyses to extend our limited knowledge regarding multicellular trichome development and metabolism in cucumber. Mict was found to be explicitly expressed within trichome cells. Transcriptomic analysis indicated that genes involved in flavonoid and cuticle metabolism are significantly downregulated in mict mutants. Further metabolomic analysis confirmed that flavonoids, lipids, and cuticle compositions are dramatically altered in mict mutants. Additional studies revealed that Mict regulates flavonoid, lipid, and cuticle biosynthesis by likely directly binding to downstream functional genes, such as CsTT4, CsFLS1, CsCER26, and CsMYB36. These findings suggest that specific metabolic pathways (e.g., flavonoids and cuticle components) are co-regulated by Mict and provide insights into transcriptional regulation mechanisms of multicellular trichome development and its specific metabolism in cucumber.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.