Evidence map›Paper›PMID 33518316›Full record

ArticlePoultry science2021

Effects of a dietary direct-fed microbial and Ferulago angulata extract on growth performance, intestinal microflora, and immune function of broiler chickens infected with Campylobacter jejuni.

Zahra Nooreh, Kamran Taherpour, Mohammad Akbari Gharaei, Hassan Shirzadi, Hossein Ali Ghasemi

Open access · goldAbstract read
In one paragraph

Article in Poultry science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Co-inoculation of broilers byMicrobiology spectrum · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zahra NoorehDepartment of Animal Science, Faculty of Agriculture, Ilam University, Ilam, Iran.
Kamran TaherpourDepartment of Animal Science, Faculty of Agriculture, Ilam University, Ilam, Iran. Electronic address: k.taherpour@ilam.ac.ir.
Mohammad Akbari GharaeiDepartment of Animal Science, Faculty of Agriculture, Ilam University, Ilam, Iran.
Hassan ShirzadiDepartment of Animal Science, Faculty of Agriculture, Ilam University, Ilam, Iran.
Hossein Ali GhasemiDepartment of Animal Science, Faculty of Agriculture and Natural Resources, Arak University, Arak 38156-8-8349, Iran.
Ilam University · IRArak University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colonization of the gastrointestinal tract by potentially pathogenic bacteria and their shedding in animal feces is a fundamental factor for both animal health and human food safety. This study was conducted to evaluate the efficacy of salinomycin (Sal), direct-fed microbial (DFM), and Ferulago angulata hydroalcoholic extract (FAE) against Campylobacter jejuni in broiler chickens in a 6-week pilot-scale study. A total of six hundred and seventy two 1-day-old broiler chickens were equally divided into 6 groups (each consisting of 8 replicates of 14 birds): negative control (NC; untreated and uninfected); positive control (PC; untreated, infected with C. jejuni); PC + Sal; PC + DFM; PC + 200 mg/kg of FAE (FAE200); or PC + 400 mg/kg of FAE (FAE400). All these groups (except NC) were challenged with C. jejuni on day 15. The results showed that all experimental treatments improved (P < 0.05) average daily gain compared with the PC group, and the best value was observed in the NC and FAE400 groups throughout the entire experimental period (day 1-42). The overall feed conversion ratio and mortality rate, as well as the population of C. jejuni (day 24 and 42) and Coliforms (day 42) in the ileum and cecum, were higher (P < 0.05) in broiler chickens fed with the PC diet than for chickens in the other groups, except those in the FAE200 group. Immune responses revealed that among challenged birds, those that were fed diets DFM and FAE400 had significantly higher IgG (day 24 and 42), IgA (day 24), IL-6 (day 24), and gamma interferon (day 24 and 42) concentrations than the PC group. In conclusion, dietary FAE, especially at a high level of inclusion in broiler diet (400 mg/kg), could beneficially influence the immune status, as well as improve growth performance and intestinal microflora under Campylobacter challenge, which was comparable to those of Sal and DFM supplements.

Indexed as

Campylobacter jejuniGastrointestinal MicrobiomeAnimal FeedAnimalsChickensDietDietary SupplementsImmunityPlant ExtractsPlant Extractsbroiler performanceCampylobacter challengeherbal extractimmune responseintestinal microflora

Identifiers

PMID33518316
PMCPMC7936196
OpenAlexW3119112242

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.