Evidence map›Paper›PMID 33517882›Full record

Trial reportBMC geriatrics2021

Factors associated with improved walking in older people during hospital rehabilitation: secondary analysis of a randomized controlled trial.

Catherine M Said, Jennifer L McGinley, Cassandra Szoeke, Barbara Workman, Keith D Hill, Joanne E Wittwer, Michael Woodward, Danny Liew, Leonid Churilov, Julie Bernhardt and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01910740 (Optimising Rehabilitation Outcomes in Frail Older Adults), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01910740 nacompletednot on this map

Optimising Rehabilitation Outcomes in Frail Older Adults: Effects of Increasing the Amount of Physical Activity

TypeinterventionalSponsorLa Trobe UniversityRan2014 to 2015Enrolled198ConditionsFrail Older People Undergoing Inpatient RehabilitationArmsEnhanced Physical Activity, Usual Care, Social Interaction
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Catherine M SaidMelbourne School of Health Sciences, The University of Melbourne, Parkville, Australia. csaid@unimelb.edu.au.
Jennifer L McGinleyMelbourne School of Health Sciences, The University of Melbourne, Parkville, Australia.
Cassandra SzoekeHealthy Ageing Program, Department of Medicine, The University of Melbourne, Centre for Medical Research, Parkville, Australia.
Barbara WorkmanRehabilitation and Aged Care Services, Monash Health, Cheltenham, Australia.
Keith D HillRehabilitation, Ageing and Independent Living (RAIL) Research Centre, School of Primary and Allied Health Care, Monash University, Peninsula Campus, McMahons Road, Frankston, Australia.
Joanne E WittwerLa Trobe Centre for Exercise and Sports Medicine Research, School of Allied Health, La Trobe University, Bundoora, Australia.
Michael WoodwardAged Care Services, Austin Health, Heidelberg, Australia.
Danny LiewSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Leonid ChurilovDepartment of Medicine (Austin Health) and Melbourne Brain Centre at Royal Melbourne Hospital, Melbourne Medical School, The University of Melbourne, Heidelberg, Australia.
Julie BernhardtStroke Division, The Florey Institute of Neuroscience and Mental Health, Heidelberg, University of Melbourne, Heidelberg, Australia.
Meg E MorrisLa Trobe Centre for Exercise and Sports Medicine Research, School of Allied Health, La Trobe University, Bundoora, Australia.

Funding

National Health and Medical Research Council 1042680
6 · The paper itself

Abstract

backgroundOlder people are often admitted for rehabilitation to improve walking, yet not everyone improves. The aim of this study was to determine key factors associated with a positive response to hospital-based rehabilitation in older people.

methodsThis was a secondary data analysis from a multisite randomized controlled trial. Older people (n= 198, median age 80.9 years, IQR 76.6- 87.2) who were admitted to geriatric rehabilitation wards with a goal to improve walking were recruited. Participants were randomized to receive additional daily physical therapy focused on mobility (n = 99), or additional social activities (n = 99). Self-selected gait speed was measured on admission and discharge. Four participants withdrew. People who changed gait speed ≥0.1 m/s were classified as 'responders' (n = 130); those that changed <0.1m/s were classified as 'non-responders' (n = 64). Multivariable logistic regression explored the association of six pre-selected participant factors (age, baseline ambulation status, frailty, co-morbidities, cognition, depression) and two therapy factors (daily supervised upright activity time, rehabilitation days) and response.

resultsResponding to rehabilitation was associated with the number of days in rehabilitation (OR 1.04; 95% CI 1.00 to 1.08; p = .039) and higher Mini Mental State Examination scores (OR 1.07, 95% CI 1.00 - 1.14; p = .048). No other factors were found to have association with responding to rehabilitation.

conclusionIn older people with complex health problems or multi-morbidities, better cognition and a longer stay in rehabilitation were associated with a positive improvement in walking speed. Further research to explore who best responds to hospital-based rehabilitation and what interventions improve rehabilitation outcomes is warranted.

trial registrationAustralian New Zealand Clinical Trials Registry ACTRN12613000884707; ClinicalTrials.gov Identifier NCT01910740 .

Indexed as

Activities of Daily LivingWalkingAgedAged, 80 and overAustraliaHumansPhysical Therapy ModalitiesTreatment OutcomeAgedAged, 80 and overExercise therapyHospitalizationMobility limitationRehabilitation

Identifiers

PMID33517882
PMCPMC7847572

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.