Evidence map›Paper›PMID 33517828›Full record

ArticleBioengineered2021

The interaction of TEA domain transcription factor 4 (TEAD4) and Yes-associated protein 1 (YAP1) promoted the malignant process mediated by serum/glucocorticoid regulated kinase 1 (SGK1).

Songlin He, Hanlu Zhang, Zongwei Xiao, Sandeep Bhushan, Ke Gao, Wenping Wang

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Vascular mimicry as a facilitator of melanoma brain metastasis.Cellular and molecular life sciences : CMLS · 2024
    Article
  7. Article
  8. Article
  9. TEAD4 as an Oncogene and a Mitochondrial Modulator.Frontiers in cell and developmental biology · 2022
    Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Songlin HeDepartment of Cardiothoracic Surgery, The Second People's Hospital of Chengdu , Chengdu, Sichuan, China.
Hanlu ZhangDepartment of Thoracic Surgery, West China Hospital of Sichuan University , Chengdu, Sichuan, China.
Zongwei XiaoDepartment of Cardiothoracic Surgery, The Second People's Hospital of Chengdu , Chengdu, Sichuan, China.
Sandeep BhushanDepartment of Cardiothoracic Surgery, The Second People's Hospital of Chengdu , Chengdu, Sichuan, China.
Ke GaoDepartment of Cardiothoracic Surgery, The Second People's Hospital of Chengdu , Chengdu, Sichuan, China.
Wenping WangDepartment of Thoracic Surgery, West China Hospital of Sichuan University , Chengdu, Sichuan, China.
Chengdu Second People's Hospital · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TEA domain transcription factor 4 (TEAD4) has been investigated to be implicated in the progression of various cancers, and it plays a role in the esophageal squamous cell carcinoma (ESCC). The study was designed to investigate how TEAD4 affected the progression of ESCC through Hippo signaling pathway

Indexed as

Adaptor Proteins, Signal TransducingDNA-Binding ProteinsImmediate-Early ProteinsMuscle ProteinsProtein Serine-Threonine KinasesTranscription FactorsAnimalsCell Line, TumorEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaGene Expression Regulation, NeoplasticHumansMaleMiceMice, Inbred BALB CMice, NudeAdaptor Proteins, Signal TransducingDNA-Binding ProteinsImmediate-Early ProteinsMuscle ProteinsProtein Serine-Threonine KinasesSerum-Glucocorticoid Regulated KinasesTEAD4 protein, humanTEA Domain Transcription FactorsTranscription FactorsYAP1 protein, humanYAP-Signaling Proteinsesophageal squamous cell carcinomasgk1TEAD4yap1

Identifiers

PMID33517828
PMCPMC8806348
OpenAlexW3126642430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.