Evidence map›Paper›PMID 33517791›Full record

ArticleDrug delivery2021

Development, optimization and characterization of nanoemulsion loaded with clove oil-naftifine antifungal for the management of tinea.

Adel F Alghaith, Sultan Alshehri, Nabil A Alhakamy, Khaled M Hosny

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Antimicrobial, Antibiofilm, and Anticancer Activities ofMolecules (Basel, Switzerland) · 2023
    Article
  5. Natural products in cosmetics.Natural products and bioprospecting · 2022
    Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Adel F AlghaithDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0001-5593-7309
Sultan AlshehriDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Nabil A AlhakamyFaculty of Pharmacy, Department of Pharmaceutics, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID https://orcid.org/0000-0002-3826-1519
Khaled M HosnyFaculty of Pharmacy, Department of Pharmaceutics, King Abdulaziz University, Jeddah, Saudi Arabia.
Alfaisal University · SABeni-Suef University · EGKing Abdulaziz University · SAKing Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tinea is a common superficial infection caused by keratinophylic fungi called dermatophytes. The objective of the current investigation was to develop and optimize a self-nanoemulsion drug delivery system (SENDDs) using clove oil loaded with naftifine (NF). Clove oil possesses good anti-inflammatory and antifungal properties that can support naftifine action. Box-Behnken designs were used to prepare plain and naftifine loaded SENDDs. The plain SENDDs were evaluated for their globule size. The medicated formulations (NF-CO-SENDDs) were characterized by measuring their globular size,

Indexed as

Administration, CutaneousAllylamineAnimalsAntifungal AgentsChemistry, PharmaceuticalClove OilDrug Delivery SystemsEmulsionsMaleNanoparticlesParticle SizePermeabilityRatsRats, WistarSkinSkin AbsorptionAllylamineAntifungal AgentsClove OilEmulsionsnaftifineSurface-Active AgentsBox–Behnkenclove oilexperimental designnaftifineNanoemulsiontinea

Identifiers

PMID33517791
PMCPMC8725874
OpenAlexW3127248977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.