Evidence map›Paper›PMID 33517678›Full record

ArticleCirculation. Genomic and precision medicine2021

Whole-Transcriptome Profiling of Human Heart Tissues Reveals the Potential Novel Players and Regulatory Networks in Different Cardiomyopathy Subtypes of Heart Failure.

Chia-Feng Liu, Ying Ni, Christine S Moravec, Michael Morley, Euan A Ashley, Thomas P Cappola, Kenneth B Margulies, W H Wilson Tang

Erratum issuedAbstract readLetter
In one paragraph

Article in Circulation. Genomic and precision medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Differential expression of members of SOX family of transcription factors in failing human hearts.Translational research : the journal of laboratory and clinical medicine · 2022
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Three Modes of Viral Adaption by the Heart.bioRxiv : the preprint server for biology · 2024
    Article
  9. Transcriptome studies of inherited dilated cardiomyopathies.Mammalian genome : official journal of the International Mammalian Genome Society · 2023
    Review
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Chia-Feng LiuDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute (C.-F.L., C.S.M., W.H.W.T.), Cleveland Clinic, OH.
Ying NiTaussig Cancer Institute (Y.N.), Cleveland Clinic, OH.
Christine S MoravecDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute (C.-F.L., C.S.M., W.H.W.T.), Cleveland Clinic, OH.
Michael MorleyPenn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia (M.M., T.P.C., K.B.M.).
Euan A AshleyDivision of Cardiovascular Medicine, Department of Medicine, Stanford University Medical Center, CA (E.A.A.).
Thomas P CappolaPenn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia (M.M., T.P.C., K.B.M.).
Kenneth B MarguliesPenn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia (M.M., T.P.C., K.B.M.).
W H Wilson TangDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute (C.-F.L., C.S.M., W.H.W.T.), Cleveland Clinic, OH.

Funding

Integrative genomics of human heart failureR01HL105993 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI ASHLEY, EUAN A, CAPPOLA, THOMAS P. · 2011 to 2014
$8.9M
What comes next? Engaging stakeholders in governance of participant data and relationships during the sunset of large genomic medicine research initiativesU01HG010218 · NHGRI · STANFORD UNIVERSITY · PI ASHLEY, EUAN A, BERNSTEIN, JONATHAN ADAM · 2018 to 2022
$6.3M
MTSS1 in Myocardial DiseaseR01HL141232 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI THOMAS P. CAPPOLA, Scott Michael Damrauer · 2019 to 2026
$4.7M
Mechanical Stress-Dependent Remodeling of the Cardiac Microtubule NetworkR01HL149891 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Kenneth Ber Margulies, Benjamin Lears Prosser · 2020 to 2026
$4.2M
Diet, Gut Microbiota, and Heart FailureR01HL126827 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI HAZEN, STANLEY L, TANG, WAI HONG WILSON · 2016 to 2019
$3.1M
Structure function relationships from deep mutational scanning in human cardiomyopathyR01HL144843 · NHLBI · STANFORD UNIVERSITY · PI ASHLEY, EUAN A · 2020 to 2023
$2.8M
NHGRI NIH HHS U01 HG010218NHLBI NIH HHS R01 HL105993NHLBI NIH HHS R01 HL126827NHLBI NIH HHS R01 HL141232NHLBI NIH HHS R01 HL144843NHLBI NIH HHS R01 HL149891
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

TranscriptomeBiomarkersCardiomyopathiesDown-RegulationGene Expression ProfilingGene Regulatory NetworksHeart FailureHeart VentriclesHumansMyocardiumPhenotypeReceptor, Notch2SemaphorinsSignal TransductionUp-RegulationBiomarkersNOTCH2 protein, humanReceptor, Notch2Sema4c protein, humanSemaphorinscardiomyopathiesgene expressionheart failurephenotypetranscriptome

Identifiers

PMID33517678
PMCPMC7887094

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.