Evidence map›Paper›PMID 33517481›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

Supportive care of cancer patients with a self-applied photobiomodulation device: a case series.

Lilach Gavish, Yehuda Zadik, Rose Raizman

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. From clinic to couch: a pilot study of home-use photobiomodulation for radiation-induced oral mucositis and dermatitis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Trial
  2. Article
  3. Self-applied photobiomodulation device: the next generation in oral mucositis prevention and treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  4. Clinical use of photobiomodulation for the prevention and treatment of oral mucositis: the real-life experience of MASCC/ISOO members.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Lilach GavishInstitute for Research in Military Medicine (IRMM), Faculty of Medicine, The Hebrew University of Jerusalem, POB 12272, 9112001, Jerusalem, Israel. lilachg@ekmd.huji.ac.il.ORCID http://orcid.org/0000-0003-0392-8958
Yehuda ZadikInstitute for Research in Military Medicine (IRMM), Faculty of Medicine, The Hebrew University of Jerusalem, POB 12272, 9112001, Jerusalem, Israel.
Rose RaizmanDepartment of Professional Practice, Scarborough Health Network, Centenary Hospital, Toronto, Canada.
Hebrew University of Jerusalem · ILUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOral mucositis (OM) and prolonged wound healing are common side-effects of cancer treatments. Photobiomodulation (PBM), previously called low-level laser, is currently part of the official guideline for OM prevention. However, all the PBM protocols relate to office-based devices, operated by professional health caregivers, requiring frequent applications. In the following case series, we present our experience with a self-applied consumer home-use PBM device for supportive care.

methodsFive patients receiving cancer treatment presented at the clinic (female:male 3:2, 55-76 years old) with OM grade 3/4 (n=2), post-surgical non-healing wounds (n=3), and dermatitis (n=1). The PBM treatment (808 nm, 250 mW peak power, 15KHz, 5 J/min, ray size 4.5×1.0cm

resultsThe treatment was found effective for resolving OM with rapid pain relief and accelerated healing in post-operative wounds and dermatitis, without reported adverse events. Patients found routine easy to follow and painless, and the protocol was easily integrated as an adjuvant treatment to standard care at the clinic or home while not requiring additional time from the staff.

conclusionsSide-effects induced by cancer therapy have a detrimental effect on the patient's well-being and may delay or even prevent the patients from completing treatment regimens. PBM is already an established tool for supportive treatment in cancer patients. The advent of a self-applied personal PBM treatment with easy-to-apply protocols for a variety of side-effects makes this technology an important accessible and safe supportive care option.

Indexed as

AgedFemaleHumansLow-Level Light TherapyMaleMiddle AgedNeoplasmsPalliative CareStomatitisCase reportDehiscence, Oral mucositisHome-useLow-level laserPhotobiomodulationSupportive care

Identifiers

PMID33517481
PMCPMC7847302
OpenAlexW3128466520

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.