Evidence map›Paper›PMID 33517324›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

Synthesis and Preclinical Evaluation of a

Stephanie Robu, Antonia Richter, Dario Gosmann, Christof Seidl, David Leung, Wendy Hayes, Daniel Cohen, Paul Morin, David J Donnelly, Daša Lipovšek and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Unveiling the potential of copper-61 vs. gallium-68 for SSTR PET imaging.European journal of nuclear medicine and molecular imaging · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. The discovery and evaluation of [European journal of nuclear medicine and molecular imaging · 2024
    Article
  12. Review
  13. Inspired by novel radiopharmaceuticals: Rush hour of nuclear medicine.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2023
    Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Novel smallFrontiers in oncology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Stephanie RobuDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; stephanie.robu@tum.de.
Antonia RichterDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Dario GosmannSchool of Medicine, Clinic and Policlinic for Internal Medicine III, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Christof SeidlDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
David LeungBristol-Myers Squibb Research and Development, Princeton, New Jersey.
Wendy HayesBristol-Myers Squibb Research and Development, Princeton, New Jersey.
Daniel CohenBristol-Myers Squibb Research and Development, Princeton, New Jersey.
Paul MorinBristol-Myers Squibb Research and Development, Princeton, New Jersey.
David J DonnellyBristol-Myers Squibb Research and Development, Princeton, New Jersey.
Daša LipovšekBristol-Myers Squibb Research and Development, Princeton, New Jersey.
Samuel J BonacorsiBristol-Myers Squibb Research and Development, Princeton, New Jersey.
Adam SmithBristol-Myers Squibb Research and Development, Princeton, New Jersey.
Katja SteigerInstitute of Pathology, School of Medicine, Technical University of Munich, Munich, Germany.
Christina AulehnerSchool of Medicine, Clinic and Policlinic for Internal Medicine III, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Angela M KrackhardtSchool of Medicine, Clinic and Policlinic for Internal Medicine III, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Wolfgang A WeberDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Bristol-Myers Squibb (United States) · USKlinikum rechts der Isar · DETechnical University of Munich · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blocking the interaction of the immune checkpoint molecule programmed cell death protein-1 and its ligand, PD-L1, using specific antibodies has been a major breakthrough for immune oncology. Whole-body PD-L1 expression PET imaging may potentially allow for a better prediction of response to programmed cell death protein-1-targeted therapies. Imaging of PD-L1 expression is feasible by PET with the adnectin protein

Indexed as

B7-H1 AntigenGallium RadioisotopesPositron-Emission TomographyAnimalsCell Line, TumorFibronectin Type III DomainGene Expression Regulation, NeoplasticHumansIsotope LabelingMiceRadiochemistryRadiopharmaceuticalsRecombinant ProteinsTissue DistributionadnectinB7-H1 AntigenCD274 protein, humanGallium-68Gallium RadioisotopesRadiopharmaceuticalsRecombinant Proteins18F-BMS-98619268Ga-adnectin68Ga-BMS-986192PD-1/PD-L1 checkpoint inhibitorsPD-L1 PET imaging

Identifiers

PMID33517324
PMCPMC8882891
OpenAlexW3128375882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.