Evidence map›Paper›PMID 33516952›Full record

ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2021

Hepatic Vasculopathy and Regenerative Responses of the Liver in Fatal Cases of COVID-19.

Barbara Kaltschmidt, Antonia D E Fitzek, Julia Schaedler, Christine Förster, Christian Kaltschmidt, Torsten Hansen, Fabian Steinfurth, Beatrice A Windmöller, Christian Pilger, Cihang Kong and 10 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. COVID-19 Infection, Drugs, and Liver Injury.Journal of clinical medicine · 2025
    Review
  4. Review
  5. In silico investigation ofJournal of ginseng research · 2023
    Article
  6. Review
  7. COVID-19 and liver injury: An ongoing challenge.World journal of gastroenterology · 2023
    Review
  8. COVID-19: Has the Liver Been Spared?International journal of molecular sciences · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Molecular mechanisms implicated in SARS-CoV-2 liver tropism.World journal of gastroenterology · 2022
    Review
  13. Review
  14. Article
  15. Article
  16. Observational
  17. Gastrointestinal, hepatic and pancreatic manifestations of COVID-19 in children.Clinics and research in hepatology and gastroenterology · 2022
    Review
  18. Article
  19. Article
  20. First case of postmortem study in a patient vaccinated against SARS-CoV-2.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 2 countries.

Barbara KaltschmidtDepartment of Cell Biology, Faculty of Biology, University of Bielefeld, Bielefeld, Germany.
Antonia D E FitzekDepartment of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Julia SchaedlerDepartment of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Christine FörsterInstitute of Pathology, KRH Hospital Nordstadt, affiliated with the University Hospital of the University of Bielefeld, Campus Bielefeld-Bethel, Hannover, Germany.
Christian KaltschmidtDepartment of Cell Biology, Faculty of Biology, University of Bielefeld, Bielefeld, Germany.
Torsten HansenInstitute of Pathology, University Hospital OWL of the University of Bielefeld, Campus Klinikum Lippe, Detmold, Germany.
Fabian SteinfurthDepartment of General and Visceral Surgery, University Hospital OWL of the University of Bielefeld, Campus Bielefeld-Bethel, Bielefeld, Germany.
Beatrice A WindmöllerDepartment of Cell Biology, Faculty of Biology, University of Bielefeld, Bielefeld, Germany.
Christian PilgerBiomolecular Photonics, Faculty of Physics, University of Bielefeld, Bielefeld, Germany.
Cihang KongBiomolecular Photonics, Faculty of Physics, University of Bielefeld, Bielefeld, Germany.
Kashika SinghDepartment of General and Visceral Surgery, University Hospital OWL of the University of Bielefeld, Campus Bielefeld-Bethel, Bielefeld, Germany.
Axel NierhausDepartment of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Dominic WichmannDepartment of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Jan SperhakeDepartment of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Klaus PüschelDepartment of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Thomas HuserBiomolecular Photonics, Faculty of Physics, University of Bielefeld, Bielefeld, Germany.
Martin KrügerDepartment of Internal Medicine and Gastroenterology, University Hospital OWL of the University of Bielefeld, Campus Bielefeld-Bethel, Bielefeld, Germany.
Simon C RobsonCenter for Inflammation Research, Department of Anesthesia and Division of Gastroenterology, Departement of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Ludwig WilkensInstitute of Pathology, KRH Hospital Nordstadt, affiliated with the University Hospital of the University of Bielefeld, Campus Bielefeld-Bethel, Hannover, Germany.
Jan Schulte Am EschDepartment of General and Visceral Surgery, University Hospital OWL of the University of Bielefeld, Campus Bielefeld-Bethel, Bielefeld, Germany. Electronic address: jan.schulteamesch@evkb.de.
Bielefeld University · DEUniversität Hamburg · DEBeth Israel Deaconess Medical Center · USKlinikum Lippe · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infects the nasopharynx and lungs and causes coronavirus disease-2019 (COVID-19). It may impact the heart, brain, kidney, and liver.

Indexed as

Acute Kidney InjuryCOVID-19HumansKidneyLiverSARS-CoV-2

Identifiers

PMID33516952
PMCPMC7844358
OpenAlexW3129002592

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.