SynthesisRespiratory research2021
Effects of exercise-based pulmonary rehabilitation on adults with asthma: a systematic review and meta-analysis.
Synthesis in Respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- British Thoracic Society quality standard for pulmonary rehabilitation.BMJ open respiratory research · 2026Guideline
- The effectiveness of physical activity in asthma management: An overview of systematic reviews.PloS one · 2025Pooled it
- Pooled it
- A systematic review of the characteristics of interventions that promote physical activity in adults with asthma.Journal of health psychology · 2022Pooled it
- Does pulmonary rehabilitation address treatable traits? A systematic review.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- Pulmonary rehabilitation versus usual care for adults with asthma.The Cochrane database of systematic reviews · 2022Pooled it
- Effects of exercise-based pulmonary rehabilitation on severe/very severe COPD: a systematic review and meta-analysis.Therapeutic advances in respiratory diseasePooled it
- Effectiveness of a home-based exercise program on functional outcomes in women with asthma: A randomized controlled trial.BMC pulmonary medicine · 2026Trial
- Breathing Exercises for Patients with Asthma in Specialist Care: A Multicenter Randomized Clinical Trial.Annals of the American Thoracic Society · 2022Trial
- The effect of the buteyko breathing technique on fatigue, exercise capacity, and asthma control in patients with asthma: a randomized controlled trial.Irish journal of medical science · 2026Article
- Effect of physical activity on pulmonary function and quality of life in asthma patients: a systematic review and meta-analysis.Frontiers in medicine · 2026Review
- Associations between physical activity levels and chronic lung diseases in middle-aged and older adults in China: A CHARLS-based study.PloS one · 2026Article
- Effects of aquatic exercise therapy on lung function in patients with asthma: a systematic review and meta-analysis.Frontiers in physiology · 2026Review
- Comprehensive Insights into Metastasis-Associated Spinal Cord Compression: Pathophysiology, Diagnosis, Treatment, and Prognosis: A State-of-the-Art Systematic Review.Journal of clinical medicine · 2024Review
- Efficacy of Digital Therapeutics for Pulmonary Rehabilitation: A Multi-Center, Randomized Controlled Trial.Life (Basel, Switzerland) · 2024Article
- Latent Classes of Personality Traits and Their Relationship with Workplace Bullying among Acute and Critical Care Nurses.Journal of nursing management · 2024Article
- Bringing the treatable traits approach to primary care asthma management.Frontiers in allergy · 2023Article
- Physical training in adults with asthma: An integrative approach on strategies, mechanisms, and benefits.Frontiers in rehabilitation sciences · 2023Review
- Can long-term regular physical activity improve health outcomes among adults with asthma-evidence from a systematic review and Bayesian meta-analysis.Annals of translational medicine · 2022Article
- Physical Training Reduces Chronic Airway Inflammation and Mediators of Remodeling in Asthma.Oxidative medicine and cellular longevity · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundPulmonary rehabilitation (PR) has been proposed as an effective method for many respiratory diseases. However, the effects of exercise-based PR on asthma are currently inconclusive. This review aimed to investigate the effects of exercise-based PR on adults with asthma.
methodsThe PubMed, Embase, Cochrane Library, Web of Science, International Clinical Trials Registry Platform and ClinicalTrials.gov databases were searched from inception to 31 July 2019 without language restriction. Randomized controlled trials (RCTs) investigating the effects of exercise-based PR on adults with asthma were included. Study selection, data extraction and risk of bias assessment were performed by two investigators independently. Meta-analysis was conducted by RevMan software (version 5.3). Evidence quality was rated by the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system.
resultsTen literatures from nine studies (n = 418 patients) were identified. Asthma quality of life questionnaire total scores (MD = 0.39, 95% CI: 0.02 to 0.76) improved significantly in the experimental group compared to control group, including activity domain scores (MD = 0.58, 95% CI: 0.21 to 0.94), symptom domain scores (MD = 0.52, 95% CI: 0.19 to 0.85), emotion domain scores (MD = 0.53, 95% CI: - 0.03 to 1.09) and environment domain scores (MD = 0.56, 95% CI: 0.00 to 1.11). Both the 6-min walk distance (MD = 34.09, 95% CI: 2.51 to 65.66) and maximum oxygen uptake (MD = 4.45, 95% CI: 3.32 to 5.58) significantly improved. However, improvements in asthma control questionnaire scores (MD = - 0.25, 95% CI: - 0.51 to 0.02) and asthma symptom-free days (MD = 3.35, 95% CI: - 0.21 to 6.90) were not significant. Moreover, there was no significant improvement (MD = 0.10, 95% CI: - 0.08 to 0.29) in forced expiratory volume in 1 s. Nonetheless, improvements in forced vital capacity (MD = 0.23, 95% CI: 0.08 to 0.38) and peak expiratory flow (MD = 0.39, 95% CI: 0.21 to 0.57) were significant.
conclusionsExercise-based PR may improve quality of life, exercise tolerance and some aspects of pulmonary function in adults with asthma and can be considered a supplementary therapy. RCTs of high quality and large sample sizes are required. CLINICAL
trial registrationThe review was registered with PROSPERO (The website is https://www.crd.york.ac.uk/prospero/ , and the ID is CRD42019147107).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.