Evidence map›Paper›PMID 33516180›Full record

ArticleBMC ophthalmology2021

Intraocular solitary extramedullary plasmacytoma presenting as unilateral anterior and intermediate uveitis preceded by refractory glaucoma.

Tom Ayton, Svetlana Cherepanoff, David Gottlieb, William A Sewell, Sandy Smith, Claire Hooper

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Tom AytonUniversity of New South Wales, Sydney, Australia. tom.ayton@hotmail.com.ORCID http://orcid.org/0000-0001-7021-175X
Svetlana CherepanoffUniversity of New South Wales, Sydney, Australia.
David GottliebWestmead Hospital, Sydney, Australia.
William A SewellUniversity of New South Wales, Sydney, Australia.
Sandy SmithWestmead Hospital, Sydney, Australia.
Claire HooperUniversity of Sydney, Sydney, Australia. cy_hoooper@hotmail.com.
The University of Sydney · AUUNSW Sydney · AUGarvan Institute of Medical Research · AUWestmead Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSolitary extramedullary plasmacytoma (SEP) is a localised proliferation of monoclonal plasma cells involving soft tissue with no or minimal bone marrow involvement and no other systemic evidence of multiple myeloma. Intraocular involvement is exceedingly rare. CASE PRESENTATION: We report a 78-year-old man who was referred with glaucoma in the right eye. He subsequently developed anterior chamber (AC) inflammation and refractory glaucoma then dense vitritis. A vitrectomy was performed with the biopsy revealing numerous plasma cells with atypical findings. In conjunction with the flow cytometry results, and a systemic work up excluding multiple myeloma, a diagnosis of SEP was made. The patient was treated with ocular external beam radiotherapy with resolution of the intraocular inflammation and control of the intraocular pressure. He remains well with no local recurrence and no development of multiple myeloma over a follow up period of 2.5 years.

conclusionsThis is the first case report of SEP presenting as intraocular inflammation without a uveal tract mass.

Indexed as

GlaucomaPlasmacytomaUveitis, IntermediateAgedBiopsyHumansMaleNeoplasm Recurrence, LocalIntraocularRefractory GlaucomaSolitary Extramedullary PlasmacytomaUveitis

Identifiers

PMID33516180
PMCPMC7846981
OpenAlexW3128093516

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.