Evidence map›Paper›PMID 33515427›Full record

ArticleSleep & breathing = Schlaf & Atmung2021

Association of serum asprosin concentrations with obstructive sleep apnea syndrome.

Jurong Ding, Shanmei Wang, Wei Tan, Xinmiao Song, Li Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jurong Ding *Department of Emergency, Tongji University Affiliated Shanghai Pulmonary Hospital, Shanghai, China.
Shanmei Wang *Department of Emergency, Tongji University Affiliated Shanghai Pulmonary Hospital, Shanghai, China.
Wei TanIntensive Care Unit of Respiratory Medicine, Tongji University Affiliated Shanghai Pulmonary Hospital, 507 Zhengmin Road, Yangpu District, Shanghai, 200433, China.
Xinmiao SongIntensive Care Unit of Respiratory Medicine, Tongji University Affiliated Shanghai Pulmonary Hospital, 507 Zhengmin Road, Yangpu District, Shanghai, 200433, China.
Li ZhangIntensive Care Unit of Respiratory Medicine, Tongji University Affiliated Shanghai Pulmonary Hospital, 507 Zhengmin Road, Yangpu District, Shanghai, 200433, China. shtjzhangli@126.com.
Shanghai Pulmonary Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAsprosin, a recently discovered adipokine, stimulates the release of hepatic glucose. The purpose of the current research was to determine the relation between serum asprosin and obstructive sleep apnea syndrome (OSAS).

methodsThe current investigation enrolled 152 patients with OSAS and 97 control subjects. Serum asprosin concentrations were measured and analyzed.

resultsHigher serum asprosin concentrations were found in patients with OSAS than in the controls. Logistic regression analysis demonstrated that serum asprosin concentrations were associated with an increased risk of OSAS. Patients with severe OSAS had significantly increased asprosin compared to mild and moderate groups. The group with moderate OSAS showed higher serum asprosin levels than the group with mild OSAS. Pearson correlation analysis demonstrated a positive relation between serum asprosin and disease severity. Simple linear regression analyses showed a significant correlation between serum asprosin with body mass index (BMI), fasting plasma glucose (FPG), homeostasis model assessment of insulin resistance (HOMA-IR), triglycerides (TG), and apnea-hypopnea index (AHI), and negatively correlated with high-density lipoprotein cholesterol (HDL-C). Multiple linear regression analysis revealed a significant correlation between serum asprosin with BMI, FPG, HOMA-IR, TG, AHI, and HDL-C.

conclusionThere is a significant correlation between serum asprosin with the presence and severity of OSAS.

Indexed as

AdipokinesAdultFemaleFibrillin-1HumansMaleMiddle AgedSleep Apnea, ObstructiveAdipokinesFBN1 protein, humanFibrillin-1AsprosinInflammationObstructive sleep apnea syndrome

Identifiers

PMID33515427
OpenAlexW3121816078

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.