Evidence map›Paper›PMID 33515219›Full record

ArticleJournal of biomedical optics2021

Dynamic properties of surfactant-enhanced laser-induced vapor bubbles for lithotripsy applications.

Nicholas C Giglio, Thomas C Hutchens, Austin A South, Nathaniel M Fried

Open access · goldAbstract read
In one paragraph

Article in Journal of biomedical optics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Nanofluid-Enhanced Laser Lithotripsy Using Conducting Polymer Nanoparticles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nicholas C GiglioUniversity of North Carolina at Charlotte, Department of Physics and Optical Science, Charlotte, Nor, United States.
Thomas C HutchensUniversity of North Carolina at Charlotte, Department of Physics and Optical Science, Charlotte, Nor, United States.
Austin A SouthUniversity of North Carolina at Charlotte, Department of Mechanical Engineering, Charlotte, North Ca, United States.
Nathaniel M FriedUniversity of North Carolina at Charlotte, Department of Physics and Optical Science, Charlotte, Nor, United States.
University of North Carolina at Charlotte · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

significanceWater is a primary absorber of infrared (IR) laser energy, and urinary stones are immersed in fluid in the urinary tract and irrigated with saline during IR laser lithotripsy. Laser-induced vapor bubbles, formed during lithotripsy, contribute to the stone ablation mechanism and stone retropulsion effects.

aimIntroduction of a surfactant may enable manipulation of vapor bubble dimensions and duration, potentially for more efficient laser lithotripsy. APPROACH: A surfactant with concentrations of 0%, 5%, and 10% was tested. A single pulse from a thulium fiber laser with wavelength of 1940 nm was delivered to the surfactant through a 200-μm-core optical fiber, using a wide range of laser parameters, including energies of 0.05 to 0.5 J and pulse durations of 250 to 2500  μs.

resultsBubble length, width, and duration with surfactant increased on average by 29%, 17%, and 120%, compared with water only.

conclusionsOur study demonstrated successful manipulation of laser-induced vapor bubble dimensions and duration using a biocompatible and commercially available surfactant. With further study, use of a surfactant may potentially improve the "popcorn" technique of laser lithotripsy within the confined space of the kidney, enable non-contact laser lithotripsy at longer working distances, and provide more efficient laser lithotripsy.

Indexed as

Lasers, Solid-StateLithotripsyLithotripsy, LaserUrinary CalculiHumansSurface-Active AgentsThuliumSurface-Active AgentsThuliumkidney stone diseaselithotripsysurfactantthulium fiber laservapor bubbles

Identifiers

PMID33515219
PMCPMC7846116
OpenAlexW3121634057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.