ArticleJournal of general internal medicine2021
Characterizing the Variation of Alcohol Cessation Pharmacotherapy in Primary Care.
Article in Journal of general internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 16 citations in OpenAlex.
- Discontinuation of medications for alcohol use disorder in the United States: Patient, prescriber and medication predictors.Addiction (Abingdon, England) · 2026Observational
- Initiation of Medications for Alcohol Use Disorder Among Hospitalized Veterans : A Retrospective Cohort Study.Annals of internal medicine · 2026Article
- Perspectives of In-Hospital Intramuscular Naltrexone and Oral Medications for Alcohol Use Disorder: A Study of Addiction Clinicians and Hospitalized Patients.Journal of general internal medicine · 2025Article
- Why is substance use missing from my patient's problem list? CTN research to advance screening, prevention, and treatment of substance use in primary care.Journal of substance use and addiction treatment · 2025Article
- Primary Care Visit Frequency Is Associated With Diagnosis But Not Pharmacotherapy Prescribing for Patients With Alcohol Use Disorder : AUD Pharmacotherapy Prescribing in Primary Care.The journal of behavioral health services & research · 2025Article
- Clinician Prescribing Practices Involving Medications for Alcohol Use Disorder.American journal of preventive medicine · 2025Article
- Receipt of Medications for Alcohol and Opioid Use Disorders: The Importance of Service Utilization Patterns.The journal of behavioral health services & research · 2025Article
- Medications for Alcohol Use Disorder: Rates and Predictors of Prescription Order and Fill in Outpatient Settings.Journal of general internal medicine · 2024Article
- Disparities in Treatment for Alcohol Use Disorder Among All of Us Participants.The American journal of psychiatry · 2024Article
- Outcomes After Initiation of Medications for Alcohol Use Disorder at Hospital Discharge.JAMA network open · 2024Article
- Pharmacologic Treatment Initiation Among Medicare Beneficiaries Hospitalized With Alcohol Use Disorder.Annals of internal medicine · 2023Article
- Epidemiology, Risk Factors, and Prevention of Head and Neck Squamous Cell Carcinoma.Medical sciences (Basel, Switzerland) · 2023Review
- Treatment for alcohol use disorder among persons with and without HIV in a clinical care setting in the United States.Drug and alcohol dependence · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlcohol use disorder (AUD) imposes a high mortality and economic burden. Effective treatment is available, though underutilized.
objectiveDescribe trends in AUD pharmacotherapy, variation in prescribing, and associated patient factors.
designRetrospective cohort using electronic health records from 2010 to 2019.
participantsPrimary care patients from 39 clinics in Ohio and Florida with diagnostic codes for alcohol dependence or abuse plus social history indicating alcohol use. PCPs in family or internal medicine with at least 20 AUD patients. MAIN MEASURES: Pharmacotherapy for AUD (naltrexone, acamprosate, and disulfiram), abstinence from alcohol, patient demographics, and comorbidities. Generalized linear mixed models were used to identify patient factors associated with prescriptions and the association of pharmacotherapy with abstinence. KEY
resultsWe identified 13,250 patients; average age was 54 years, 66.9% were male, 75.0% were White, and median household income was $51,776 per year. Over 10 years, the prescription rate rose from 4.4 to 5.6%. Patients who were Black (aOR 0.74; 95% CI 0.58, 0.94) and insured by Medicare versus commercial insurance (aOR 0.61; 95% CI 0.48, 0.78) were less likely to be treated. Higher median household income ($10,000 increment, aOR 1.06; 95% CI 1.03, 1.10) and Medicaid versus commercial insurance (aOR 1.52; 95% CI 1.24, 1.87) were associated with treatment. Receiving pharmacotherapy was associated with subsequent documented abstinence from alcohol (aOR 1.60; 95% CI 1.33, 1.92). We identified 236 PCPs. The average prescription rate was 3.6% (range 0 to 24%). The top decile prescribed to 14.6% of their patients. The bottom 4 deciles had no prescriptions. Family physicians had higher rates of pharmacotherapy than internists (OR 1.50; 95% CI 1.21, 1.85).
conclusionsMedications for AUD are infrequently prescribed, but there is considerable variation among PCPs. Increasing the use of pharmacotherapy by non-prescribers may increase abstinence from alcohol.
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