Evidence map›Paper›PMID 33515106›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

Associations between baseline demographic, clinical and lifestyle factors, and changes in fatigue, depression, and health-related quality of life in long-term cancer survivors: a cohort study.

Shannen R van der Kruk, Kate M Gunn, Ilse Mesters, Brigid M Lynch, Jeff K Vallance, Terry Boyle

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Shannen R van der KrukDepartment of Epidemiology, Maastricht University, Maastricht, the Netherlands.
Kate M GunnCancer Research Institute, University of South Australia, Adelaide, SA, Australia.
Ilse MestersDepartment of Epidemiology, Maastricht University, Maastricht, the Netherlands.
Brigid M LynchCancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia.
Jeff K VallanceFaculty of Health Disciplines, Athabasca University, Athabasca, AB, Canada.
Terry BoyleAustralian Centre for Precision Health, University of South Australia, Adelaide, SA, Australia. Terry.Boyle@unisa.edu.au.ORCID http://orcid.org/0000-0001-6741-330X
University of South Australia · AUAthabasca University · CABaker Heart and Diabetes Institute · AUMaastricht University · NL

Funding

Victorian Cancer Agency MCRF18005
6 · The paper itself

Abstract

purposeTo investigate the longitudinal associations between demographic, clinical and lifestyle factors, and changes in patient-reported outcomes (PROs) in cancer survivors 6-9 years post-diagnosis in Western Australia.

methodsA total of 290 individuals participated in this study. Three-quarters of participants were female, and 55%, 31%, and 14% were survivors of breast cancer, colon cancer, and non-Hodgkin lymphoma (NHL), respectively. PROs (fatigue, depression, and health-related quality of life (HRQOL)) were reported at two time points (2012-13 and 2017). Descriptive statistics were used to assess the overall changes over time and linear mixed models were used to identify factors associated with changes over time, after adjusting for confounders.

resultsNo significant changes were observed in PROs between time point 1 and follow-up at the population level, yet a notable proportion of participants (23% for fatigue, 10% for depression, and 39% for HRQOL) reported a negative minimal clinically important difference (MCID). Being non-Caucasian and having had NHL were associated with negative changes over time. Being obese and having had radiotherapy were related to improved outcomes.

conclusionCancer survivors whose levels of fatigue, depression, and quality of life are compromised during cancer treatment may require intervention even 6-9 years post-treatment. Our results suggest particular attention should be paid to those who are non-Caucasian and who have had NHL. This is crucial for providing appropriate care and to support those who are at increased risk of deteriorating naturally over time.

Indexed as

AdolescentAdultAgedAged, 80 and overCancer SurvivorsCohort StudiesDepressionFatigueFemaleHumansLongitudinal StudiesMaleMiddle AgedQuality of LifeYoung AdultCancerDepressionFatigueOncologyQuality of lifeSurvivor

Identifiers

PMID33515106
OpenAlexW3122581101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.