Evidence map›Paper›PMID 33515047›Full record

ArticleAnnals of hematology2021

Risk factors and predictors of treatment responses and complications in immune thrombocytopenia.

Shin Yeu Ong, Chuen Wen Tan, Vajjhala Ramya, Aisyah A Malik, Xiu Hue Lee, Jordan C C Hwang, Yong Yang, Heng Joo Ng, Lai Heng Lee

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of hematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Shin Yeu OngDepartment of Haematology, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore. ong.shin.yeu@singhealth.com.sg.ORCID http://orcid.org/0000-0003-0192-6975
Chuen Wen TanDepartment of Haematology, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.
Vajjhala RamyaDepartment of Internal Medicine, Singapore General Hospital, Singapore, Singapore.
Aisyah A MalikMacquarie University, Sydney, Australia.
Xiu Hue LeeDepartment of Haematology, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.
Jordan C C HwangDepartment of Haematology, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.
Yong YangDepartment of Haematology, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.
Heng Joo NgDepartment of Haematology, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.
Lai Heng LeeDepartment of Haematology, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.
Singapore General Hospital · SGMacquarie University · AUSingHealth · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Management of adult patients with immune thrombocytopenia (ITP) is often unsatisfactory, due to variable efficacy of treatment, risk of life-threatening bleeding if disease control is poor, and side effects associated with treatment. Lack of data on the platelet count threshold associated with bleeding and infection risk associated with ITP treatment limits risk/benefit clinical decision making. We reviewed medical records of all ITP patients who were admitted to our hospital between 2012 and 2017 to evaluate the platelet count threshold for bleeding, infection burden associated with treatment, and real-world efficacy of second-line treatment. We demonstrated fair discrimination between platelet count and occurrence of bleeding, with 15 × 10

Indexed as

Drug-Related Side Effects and Adverse ReactionsAdrenal Cortex HormonesAdultAgedAged, 80 and overBlood PlateletsCohort StudiesFemaleFollow-Up StudiesHemorrhageHospitalizationHumansImmunoglobulins, IntravenousInfectionsMaleMiddle AgedAdrenal Cortex HormonesImmunoglobulins, IntravenousRituximabBleedingImmune thrombocytopeniaInfectionSecond-line therapy

Identifiers

PMID33515047
OpenAlexW3124013432

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.